Evidence map›Paper›PMID 31565221›Full record

ArticleBiomedical reports2019

Levels of nitric oxide metabolites, adiponectin and endothelin are associated with SNPs of the adiponectin and endothelin genes.

Nadezhda G Gumanova, Marina V Klimushina, Stepan A Smetnev, Anna V Kiseleva, Olga P Skirko, Alexey N Meshkov, Artem S Shanoyan, Alexander Y Kots, Victoria A Metelskaya

Open access · diamondAbstract read
In one paragraph

Article in Biomedical reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Nadezhda G GumanovaNational Medical Research Center for Preventive Medicine, Ministry of Healthcare of The Russian Federation, Moscow 101990, Russia.
Marina V KlimushinaNational Medical Research Center for Preventive Medicine, Ministry of Healthcare of The Russian Federation, Moscow 101990, Russia.
Stepan A SmetnevNational Medical Research Center for Preventive Medicine, Ministry of Healthcare of The Russian Federation, Moscow 101990, Russia.
Anna V KiselevaNational Medical Research Center for Preventive Medicine, Ministry of Healthcare of The Russian Federation, Moscow 101990, Russia.
Olga P SkirkoNational Medical Research Center for Preventive Medicine, Ministry of Healthcare of The Russian Federation, Moscow 101990, Russia.
Alexey N MeshkovNational Medical Research Center for Preventive Medicine, Ministry of Healthcare of The Russian Federation, Moscow 101990, Russia.
Artem S ShanoyanNational Medical Research Center for Preventive Medicine, Ministry of Healthcare of The Russian Federation, Moscow 101990, Russia.
Alexander Y KotsDepartment of Clinical Pharmacology, Sechenov First Moscow State Medical University, Moscow 119992, Russia.
Victoria A MetelskayaNational Medical Research Center for Preventive Medicine, Ministry of Healthcare of The Russian Federation, Moscow 101990, Russia.
National Research Center for Preventive Medicine · RUMinistry of Health of the Russian Federation · RUSechenov University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adiponectin, endothelin and nitric oxide (NO) are major regulators of vascular function. An imbalance of vasoactive factors contributes to the onset and progression of atherosclerosis. Various single nucleotide polymorphisms (SNPs) are considered to be risk factors for coronary heart disease. However, the molecular mechanisms of their associations with the components of endothelial dysfunction are poorly understood. In the present study, rs17366743, rs17300539, rs266729, rs182052 and rs2241766 SNPs of the adiponectin (

Indexed as

adiponectincardiovascular mortalitycoronary atherosclerosisendothelial dysfunctionendothelinnitric oxidepatientssingle nucleotide polymorphism

Identifiers

PMID31565221
PMCPMC6759535
OpenAlexW2971956287

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.