Evidence map›Paper›PMID 31569730›Full record

ReviewInternational journal of molecular sciences2019

Plant DNA Polymerases.

Jose-Antonio Pedroza-Garcia, Lieven De Veylder, Cécile Raynaud

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. The tomato gene Ty-6, encoding DNA polymerase delta subunit 1, confers broad resistance to Geminiviruses.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Genome-wide association study of soybean (Frontiers in plant science · 2023
    Article
  9. Article
  10. DNA polymerase epsilon binds histone H3.1-H4 and recruits MORC1 to mediate meiotic heterochromatin condensation.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. DNA polymerase epsilon interacts with SUVH2/9 to repress the expression of genes associated with meiotic DSB hotspot inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  12. Review
  13. A Mutation in DNA Polymerase α RescuesInternational journal of molecular sciences · 2021
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Jose-Antonio Pedroza-GarciaDepartment of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium. joseantonio.pedrozagarcia@psb.vib-ugent.be.ORCID 0000-0001-8258-0157
Lieven De VeylderDepartment of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium. livey@psb.vib-ugent.be.ORCID 0000-0003-1150-4426
Cécile RaynaudInstitute of Plant Sciences Paris-Saclay (IPS2), CNRS, INRA, University Paris-Sud, University of Evry, University Paris-Diderot, Sorbonne Paris-Cite, University of Paris-Saclay, Batiment 630, 91405 Orsay, France. cecile.raynaud@ips2.universite-paris-saclay.fr.ORCID 0000-0002-5231-8120
Ghent University · BEUniversité Paris-Sud · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maintenance of genome integrity is a key process in all organisms. DNA polymerases (Pols) are central players in this process as they are in charge of the faithful reproduction of the genetic information, as well as of DNA repair. Interestingly, all eukaryotes possess a large repertoire of polymerases. Three protein complexes, DNA Pol α, δ, and ε, are in charge of nuclear DNA replication. These enzymes have the fidelity and processivity required to replicate long DNA sequences, but DNA lesions can block their progression. Consequently, eukaryotic genomes also encode a variable number of specialized polymerases (between five and 16 depending on the organism) that are involved in the replication of damaged DNA, DNA repair, and organellar DNA replication. This diversity of enzymes likely stems from their ability to bypass specific types of lesions. In the past 10-15 years, our knowledge regarding plant DNA polymerases dramatically increased. In this review, we discuss these recent findings and compare acquired knowledge in plants to data obtained in other eukaryotes. We also discuss the emerging links between genome and epigenome replication.

Indexed as

DNA ReplicationDNA DamageDNA-Directed DNA PolymeraseDNA RepairEpigenomicsGenome, PlantMeiosisPlantsProtein SubunitsReplication OriginSignal TransductionStress, PhysiologicalDNA-Directed DNA PolymeraseProtein SubunitsDNA repairDNA replication

Identifiers

PMID31569730
PMCPMC6801657
OpenAlexW2976257249

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.