Evidence map›Paper›PMID 31570002›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Serine-47 phosphorylation of cytochrome

Hasini A Kalpage, Asmita Vaishnav, Jenney Liu, Ashwathy Varughese, Junmei Wan, Alice A Turner, Qinqin Ji, Matthew P Zurek, Alexandr A Kapralov, Valerian E Kagan and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Cardiac Tyrosine 97 Phosphorylation of CytochromeInternational journal of molecular sciences · 2025
    Article
  7. CytochromeSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Altered conformational dynamics contribute to species-specific effects of cytochrome c mutations on caspase activation.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. De novo sequencing and construction of a unique antibody for the recognition of alternative conformations of cytochromeProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 3 countries.

Hasini A KalpageCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, USA.
Asmita VaishnavDepartment of Biochemistry, Microbiology, and Immunology, Wayne State University, Detroit, Michigan, USA.
Jenney LiuCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, USA.
Ashwathy VarugheseCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, USA.
Junmei WanCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, USA.
Alice A TurnerCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, USA.
Qinqin JiDepartment of Chemistry, Brown University, Providence, Rhode Island, USA.
Matthew P ZurekCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, USA.
Alexandr A KapralovDepartment of Environmental and Occupational Health, Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Valerian E KaganDepartment of Environmental and Occupational Health, Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Joseph S BrunzelleCenter for Synchrotron Research, Northwestern University, Argonne, Illinois, USA.
Maurice-Andre RecanatiCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, USA.
Lawrence I GrossmanCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, USA.
Thomas H SandersonDepartment of Emergency Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Icksoo LeeCollege of Medicine, Dankook University, Cheonan-si, South Korea.
Arthur R SalomonDepartment of Chemistry, Brown University, Providence, Rhode Island, USA.
Brian F P EdwardsDepartment of Biochemistry, Microbiology, and Immunology, Wayne State University, Detroit, Michigan, USA.
Maik HüttemannCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, USA.
Wayne State University · USBrown University · USUniversity of Pittsburgh · USDankook University · KRNorthwestern University · USUniversity of Michigan–Ann Arbor · US

Funding

Infant NeuroLUX: A Novel Non-invasive Therapeutic Device for Neonatal Hypoxic Brain InjuryR42NS105238 · NINDS · MITOVATION, INC. · PI HUETTEMANN, MAIK, SANDERSON, THOMAS HUDSON · 2018 to 2020
$1.8M
The molecular basis of cardiolipin-protein interactions implicated in intrinsic apoptosisR01GM113908 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAGAN, VALERIAN E · 2016 to 2019
$1.5M
Control of Cell Respiration and Apoptosis by Phosphorylation of Cytochrome cR01GM116807 · NIGMS · WAYNE STATE UNIVERSITY · PI HUETTEMANN, MAIK · 2017 to 2020
$1.5M
Limiting brain reperfusion injury by controlling mitochondrial functionR01NS091242 · NINDS · WAYNE STATE UNIVERSITY · PI HUETTEMANN, MAIK, SANDERSON, THOMAS HUDSON · 2015 to 2018
$1.3M
NIGMS NIH HHS R01 GM113908NIGMS NIH HHS R01 GM116807NINDS NIH HHS R01 NS091242NINDS NIH HHS R42 NS105238
6 · The paper itself

Abstract

Cytochrome

Indexed as

AnimalsApoptosisBrainCaspase 3Cell RespirationCrystallography, X-RayCytochromes cElectron Transport Complex IVMembrane Potential, MitochondrialMitochondriaMolecular Dynamics SimulationMutagenesis, Site-DirectedMutationOxidation-ReductionPhosphorylationProtein ConformationCaspase 3Cytochromes cElectron Transport Complex IVReactive Oxygen SpeciesSerineapoptosiselectron transport chainischemiarespirationsignaling

Identifiers

PMID31570002
PMCPMC6894086
OpenAlexW2978056756

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.