Evidence map›Paper›PMID 31585510›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Elimination of human folypolyglutamate synthetase alters programming and plasticity of somatic cells.

Avinash C Srivastava, Yesenia Guadalupe Thompson, Jyotsana Singhal, Jordan Stellern, Anviksha Srivastava, Juan Du, Timothy R O'Connor, Arthur D Riggs

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Transcriptome Analysis Reveals the Role of Sucrose in the Production ofInternational journal of molecular sciences · 2024
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Avinash C SrivastavaDepartment of Diabetes Complications and Metabolism, City of Hope National Medical Center, Duarte, California, USA.
Yesenia Guadalupe ThompsonDepartment of Cancer Biology, City of Hope National Medical Center, Duarte, California, USA.
Jyotsana SinghalDepartment of Diabetes Complications and Metabolism, City of Hope National Medical Center, Duarte, California, USA.
Jordan StellernDepartment of Cancer Biology, City of Hope National Medical Center, Duarte, California, USA.
Anviksha SrivastavaDepartment of Cancer Biology, City of Hope National Medical Center, Duarte, California, USA.
Juan DuIntegrative Genomics Core Facility, City of Hope National Medical Center, Duarte, California, USA.
Timothy R O'ConnorDepartment of Cancer Biology, City of Hope National Medical Center, Duarte, California, USA.
Arthur D RiggsDepartment of Diabetes Complications and Metabolism, City of Hope National Medical Center, Duarte, California, USA.
City Of Hope National Medical Center · US

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI John Charles Williams · 1985 to 2026
$86.3M
NCI NIH HHS P30 CA033572
6 · The paper itself

Abstract

Folates are vital cofactors for the regeneration of

Indexed as

Cell DifferentiationCell DivisionCell LineCell PlasticityCell ProliferationDNA MethylationFolic Acidgamma-Aminobutyric AcidGene ExpressionGenes, HomeoboxGlutamic AcidHEK293 CellsHumansMetabolic Networks and PathwaysMyocytes, CardiacNanog Homeobox ProteinFolic Acidfolylpolyglutamate synthetasegamma-Aminobutyric AcidGlutamic AcidNanog Homeobox ProteinOctamer Transcription Factor-3Peptide SynthasesS-AdenosylmethionineSex-Determining Region Y ProteinC1 metabolismCRISPR/Cas9GABAglutamate-induced pluripotency

Identifiers

PMID31585510
PMCPMC6894074
OpenAlexW2979250812

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.