Evidence map›Paper›PMID 31597684›Full record

ArticleThe Journal of general physiology2019

Quantitative determination of cellular [Na

Jan Meyer, Verena Untiet, Christoph Fahlke, Thomas Gensch, Christine R Rose

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of general physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Spatiotemporal Dynamics of Lateral NaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  5. Spatio-temporal dynamics of lateral NabioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. In Vitro Effect of 9,9'-Norharmane Dimer against Herpes Simplex Viruses.International journal of molecular sciences · 2024
    Article
  9. Rapid Fluorescence Lifetime Imaging Reveals That TRPV4 Channels Promote Dysregulation of Neuronal NaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  10. Activation and Role of Astrocytes in Ischemic Stroke.Frontiers in cellular neuroscience · 2021
    Review
  11. Spike Activity Regulates Vesicle Filling at a Glutamatergic Synapse.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jan MeyerInstitute of Neurobiology, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Verena UntietInstitute of Complex Systems 4 (ICS-4), Zelluläre Biophysik, Forschungszentrum Jülich, Jülich, Germany.
Christoph FahlkeInstitute of Complex Systems 4 (ICS-4), Zelluläre Biophysik, Forschungszentrum Jülich, Jülich, Germany.ORCID 0000-0001-8602-9952
Thomas GenschInstitute of Complex Systems 4 (ICS-4), Zelluläre Biophysik, Forschungszentrum Jülich, Jülich, Germany.ORCID 0000-0002-3903-4705
Christine R RoseInstitute of Neurobiology, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Düsseldorf, Germany rose@hhu.de.ORCID 0000-0002-9684-3592
Forschungszentrum Jülich · DEHeinrich Heine University Düsseldorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorescence lifetime imaging microscopy (FLIM) with fluorescent ion sensors enables the measurement of ion concentrations based on the detection of photon emission events after brief excitation with a pulsed laser source. In contrast to intensity-based imaging, it is independent of dye concentration, photobleaching, or focus drift and has thus been successfully employed for quantitative analysis of, e.g., calcium levels in different cell types and cellular microdomains. Here, we tested the suitability of CoroNaGreen for FLIM-based determination of sodium concentration ([Na

Indexed as

Fluorescent DyesHEK293 CellsHumansHydrogen-Ion ConcentrationLasersOptical ImagingSodiumFluorescent DyesSodium

Identifiers

PMID31597684
PMCPMC6829561
OpenAlexW2979734069

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.