Evidence map›Paper›PMID 31601616›Full record

ArticleGenes & development2019

Hi-C guided assemblies reveal conserved regulatory topologies on X and autosomes despite extensive genome shuffling.

Gina Renschler, Gautier Richard, Claudia Isabelle Keller Valsecchi, Sarah Toscano, Laura Arrigoni, Fidel Ramírez, Asifa Akhtar

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Functional genomics in Spiralia.Briefings in functional genomics · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Gina RenschlerMax Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg im Breisgau, Germany.ORCID 0000-0002-6382-9815
Gautier RichardMax Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg im Breisgau, Germany.ORCID 0000-0003-3663-4569
Claudia Isabelle Keller ValsecchiMax Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg im Breisgau, Germany.ORCID 0000-0003-4135-5927
Sarah ToscanoMax Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg im Breisgau, Germany.ORCID 0000-0003-0387-366X
Laura ArrigoniMax Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg im Breisgau, Germany.ORCID 0000-0002-3626-4468
Fidel RamírezMax Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg im Breisgau, Germany.ORCID 0000-0002-9142-417X
Asifa AkhtarMax Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg im Breisgau, Germany.ORCID 0000-0001-8973-6193
Max Planck Institute of Immunobiology and Epigenetics · DEInstitut Agro Rennes-Angers · FRUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome rearrangements that occur during evolution impose major challenges on regulatory mechanisms that rely on three-dimensional genome architecture. Here, we developed a scaffolding algorithm and generated chromosome-length assemblies from Hi-C data for studying genome topology in three distantly related

Indexed as

Evolution, MolecularAlgorithmsAnimalsChromosomes, InsectConserved SequenceDosage Compensation, GeneticDrosophilaEmbryo, NonmammalianGene Expression RegulationGenome, Insectchromosome topologydosage compensationHiCX chromosome

Identifiers

PMID31601616
PMCPMC6824461
OpenAlexW2979931451

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.