Evidence map›Paper›PMID 31604781›Full record

Observational studyBMJ open2019

The Manitoba Personalized Lifestyle Research (TMPLR) study protocol: a multicentre bidirectional observational cohort study with administrative health record linkage investigating the interactions between lifestyle and health in Manitoba, Canada.

Dylan Mackay, Rebecca C Mollard, Matthew Granger, Sharon Bruce, Heather Blewett, Jared Carlberg, Todd Duhamel, Peter Eck, Patrick Faucher, Naomi C Hamm and 8 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03674957 (The Manitoba Personalized Lifestyle Research), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03674957 terminatednot on this map

The Manitoba Personalized Lifestyle Research (TMPLR) Study

TypeobservationalSponsorUniversity of ManitobaRan2016 to 2019Enrolled840ConditionsDiabetes, Cardiovascular Diseases, Chronic Kidney Diseases
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 1 country.

Dylan MackayCommunity Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0002-0751-1634
Rebecca C MollardDepartment of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Matthew GrangerDepartment of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Sharon BruceCommunity Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Heather BlewettDepartment of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Jared CarlbergDepartment of Agribusiness and Agricultural Economics, University of Manitoba, Winnipeg, Manitoba, Canada.
Todd DuhamelHealth, Leisure and Human Performance Research Institute, University of Manitoba, Winnipeg, Manitoba, Canada.
Peter EckDepartment of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Patrick FaucherGeorge and Fay Yee Centre for Healthcare Innovation, Winnipeg, Manitoba, Canada.
Naomi C HammGeorge and Fay Yee Centre for Healthcare Innovation, Winnipeg, Manitoba, Canada.
Ehsan KhafipourDepartment of Animal Science, University of Manitoba, Winnipeg, Manitoba, Canada.
Lisa LixCommunity Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Diana McMillanHealth, Leisure and Human Performance Research Institute, University of Manitoba, Winnipeg, Manitoba, Canada.
Semone MyrieDepartment of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Amir RavandiInstitute of Cardiovascular Sciences, St. Boniface General Hospital Albrechtsen Research Centre, Winnipeg, Manitoba, Canada.
Navdeep TangriDepartment of Internal Medicine, University of Manitoba College of Medicine, Winnipeg, Manitoba, Canada.
Meghan AzadChildren's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada.
Peter Jh JonesDepartment of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
University of Manitoba · CAGeorge & Fay Yee Centre for Healthcare Innovation · CAChildren's Hospital Research Institute of Manitoba · CASt. Boniface Hospital · CAAgriculture and Agri-Food Canada · CAResearch Manitoba · CASeven Oaks General Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLifestyle factors, such as diet, physical activity and sleep, are associated with the development of many chronic diseases. The objective of The Manitoba Personalized Lifestyle Research study is to understand how these lifestyle factors interact with each other and with other factors, such as an individual's genetics and gut microbiome, to influence health.

methodsAn observational study of adults, with extensive phenotyping by objective health and lifestyle assessments, and retrospective assessment of early life experiences, with retrospective and prospective utilisation of secondary data from administrative health records. STUDY POPULATION: A planned non-random convenience sample of 840 Manitobans aged 30-46 recruited from the general population, stratified by sex (equal men and women), body mass index (BMI; 60% of participants with a BMI>25 kg/m MEASUREMENTS: Lifestyle factors assessed will include dietary pattern, physical activity, cardiovascular fitness, and sleep. Factors such as medical history, socioeconomic status, alcohol and tobacco consumption, cognition, stress, anxiety, and early life experiences will also be documented. A maternal survey will be performed. Body composition and bone density will be measured by dual energy X-ray absorptiometry. Blood pressure, pulse wave velocity, and augmentation index will be measured on two consecutive days. Chronic disease risk biomarkers will be measured in blood and urine samples. DNA will be extracted for genetic analysis. A faecal sample will be collected for microbiome analysis. Participants may provide their Manitoba personal health information number to link their study data with administrative health records. ETHICS AND DISSEMINATION: Ethics approval has been obtained from the University of Manitoba Health Research Ethics Board (protocol # HS18951; 05/01/2016). Data analysis, release of results and publication of manuscripts are scheduled to start in early 2019. Additional information at www.TMPLR.ca. TRIAL REGISTRATION NUMBER: NCT03674957; Pre-results.

Indexed as

Health BehaviorHealth StatusLife StyleAdultCohort StudiesFemaleHumansMaleManitobaMedical Record LinkageMiddle Agednutritionphysical activity

Identifiers

PMID31604781
PMCPMC6797260
OpenAlexW2979680455

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.