Evidence map›Paper›PMID 31608673›Full record

ArticleAmerican journal of physiology. Renal physiology2019

Sympathetic regulation of NCC in norepinephrine-evoked salt-sensitive hypertension in Sprague-Dawley rats.

Alissa A Frame, Franco Puleo, Kiyoung Kim, Kathryn R Walsh, Elizabeth Faudoa, Robert S Hoover, Richard D Wainford

Open access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Renal interoception in health and disease.Autonomic neuroscience : basic & clinical · 2024
    Review
  8. Article
  9. Review
  10. Article
  11. Salt and Gut Microbiota in Heart Failure.Current hypertension reports · 2023
    Review
  12. Central GαiFrontiers in endocrinology · 2022
    Review
  13. βAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2021
    Review
  14. Article
  15. American journal of physiology. Renal physiology · 2020
    Article
  16. Article
  17. Hypothalamic Paraventricular Nucleus GαiHypertension (Dallas, Tex. : 1979) · 2020
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alissa A FrameDepartment of Pharmacology and Experimental Therapeutics and the Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts.
Franco PuleoDepartment of Pharmacology and Experimental Therapeutics and the Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts.
Kiyoung KimDepartment of Pharmacology and Experimental Therapeutics and the Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts.
Kathryn R WalshDepartment of Pharmacology and Experimental Therapeutics and the Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts.
Elizabeth FaudoaCollege of Arts and Sciences, Boston University, Boston, Massachusetts.
Robert S HooverResearch Service, Atlanta Veterans Affairs Medical Center, Decatur, Georgia.
Richard D WainfordDepartment of Pharmacology and Experimental Therapeutics and the Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts.
Boston University · USEmory University · US

Funding

TRAINING IN BIOMOLECULAR PHARMACOLOGYT32GM008541 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FARB, DAVID H · 1997 to 2022
$5.2M
Central mechanisms and novel biomarkers of the salt-sensitivity of blood pressureR01HL141406 · NHLBI · EMORY UNIVERSITY · PI WAINFORD, RICHARD DAVID · 2018 to 2021
$2.8M
Neural control of the kidney and long-term blood pressure regulationR01HL139867 · NHLBI · EMORY UNIVERSITY · PI WAINFORD, RICHARD DAVID · 2018 to 2021
$2.6M
Brain G-alpha subunit protein mediated neural control of blood pressureR01HL107330 · NHLBI · LSU HEALTH SCIENCES CENTER · PI WAINFORD, RICHARD DAVID · 2011 to 2015
$1.9M
Aging and hypertension: Integrated renal and sympathetic control of blood pressureR56AG057687 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WAINFORD, RICHARD DAVID · 2018 to 2018
$731k
Brain G-alpha subunit protein mediated neural control of blood pressureK02HL112718 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WAINFORD, RICHARD DAVID · 2013 to 2017
$577k
Renal and Neural Mechanisms of Age-Related HypertensionF31DK116501 · NIDDK · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FRAME, ALISSA A · 2017 to 2018
$92k
BLRD VA I01 BX002322NHLBI NIH HHS K02 HL112718NHLBI NIH HHS R01 HL107330NHLBI NIH HHS R01 HL139867NHLBI NIH HHS R01 HL141406NIA NIH HHS R56 AG057687NIDDK NIH HHS F31 DK116501NIGMS NIH HHS T32 GM008541
6 · The paper itself

Abstract

Salt sensitivity of blood pressure is characterized by inappropriate sympathoexcitation and renal Na

Indexed as

NorepinephrineAdrenergic alpha-1 Receptor AntagonistsAdrenergic beta-AntagonistsAnimalsHypertensionKidneyMaleProtein Serine-Threonine KinasesRatsRats, Sprague-DawleyReceptors, Adrenergic, alpha-1Receptors, Adrenergic, betaSodium, DietarySolute Carrier Family 12, Member 3Sympathetic Nervous SystemAdrenergic alpha-1 Receptor AntagonistsAdrenergic beta-AntagonistsNorepinephrinePAS domain kinasesProtein Serine-Threonine KinasesReceptors, Adrenergic, alpha-1Receptors, Adrenergic, betaSodium, DietarySolute Carrier Family 12, Member 3Wnk4 protein, ratadrenoceptorsblood pressurenorepinephrinesalt-sensitive hypertensionsodium-chloride cotransporter

Identifiers

PMID31608673
PMCPMC6960786
OpenAlexW2980628935

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.