Evidence map›Paper›PMID 31619551›Full record

ArticleJournal of virology2019

Limited Intrahost Diversity and Background Evolution Accompany 40 Years of Canine Parvovirus Host Adaptation and Spread.

Ian E H Voorhees, Hyunwook Lee, Andrew B Allison, Robert Lopez-Astacio, Laura B Goodman, Oyebola O Oyesola, Olutayo Omobowale, Olusegun Fagbohun, Edward J Dubovi, Susan L Hafenstein and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 84 citations in OpenAlex.

  1. Distinct evolutionary patterns of endemic and emerging parvoviruses and the origin of a new pandemic virus.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  7. Red Foxes (Microorganisms · 2025
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  9. Structures and functions of the limited natural polyclonal antibody response to parvovirus infection.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Ian E H VoorheesBaker Institute for Animal Health, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Hyunwook LeeHuck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania, USA.
Andrew B AllisonBaker Institute for Animal Health, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.ORCID 0000-0003-0971-1215
Robert Lopez-AstacioBaker Institute for Animal Health, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Laura B GoodmanDepartment of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Oyebola O OyesolaBaker Institute for Animal Health, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Olutayo OmobowaleDepartment of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
Olusegun FagbohunDepartment of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
Edward J DuboviDepartment of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Susan L HafensteinHuck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania, USA.
Edward C HolmesMarie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Life & Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0001-9596-3552
Colin R ParrishBaker Institute for Animal Health, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA crp3@cornell.edu.ORCID 0000-0002-1836-6655
Cornell University · USUniversity of Ibadan · NGPennsylvania State University · USThe University of Sydney · AU

Funding

The Evolutionary and Biological Bases of Host Switching in VirusesR01GM080533 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI PARRISH, COLIN R. · 2007 to 2019
$4.1M
Structural Controls of Functional Receptor and Antibody Binding to Viral Capsids.R01AI092571 · NIAID · CORNELL UNIVERSITY · PI PARRISH, COLIN R. · 2011 to 2021
$4.0M
Adapting molecular food safety tests to alternative matricesU18FD005144 · FDA · CORNELL UNIVERSITY · PI GOODMAN, LAURA BRUNENGRABER · 2014 to 2019
$516k
Capacity for accredited pathogen WGS in veterinary diagnosticsU18FD006448 · FDA · CORNELL UNIVERSITY · PI GOODMAN, LAURA BRUNENGRABER · 2018 to 2018
$73k
FDA HHS U18 FD005144FDA HHS U18 FD006448NIAID NIH HHS R01 AI092571NIGMS NIH HHS R01 GM080533
6 · The paper itself

Abstract

Canine parvovirus (CPV) is a highly successful pathogen that has sustained pandemic circulation in dogs for more than 40 years. Here, integrating full-genome and deep-sequencing analyses, structural information, and

Indexed as

Genome, ViralAdaptation, PhysiologicalAnimalsBiological EvolutionCapsid ProteinsDNA, ViralDog DiseasesDogsFoxesHost SpecificityModels, MolecularMutationParvoviridae InfectionsParvovirus, CaninePhylogenyProtein ConformationCapsid ProteinsDNA, ViralViral Nonstructural Proteinscanine parvovirusdeep sequencingviral cross-species transmissionviral evolutionviral host adaptionviral intrahost diversity

Identifiers

PMID31619551
PMCPMC6912114
OpenAlexW2979701347

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.