Evidence map›Paper›PMID 31620011›Full record

ArticleFrontiers in physiology2019

Android Fat Deposition and Its Association With Cardiovascular Risk Factors in Overweight Young Males.

Carolina Ika Sari, Nina Eikelis, Geoffrey A Head, Markus Schlaich, Peter Meikle, Gavin Lambert, Elisabeth Lambert

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 46 citations in OpenAlex.

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  7. ANDROID and A/G ratio are correlated with sarcopenia among type 2 diabetes patients.Therapeutic advances in endocrinology and metabolism · 2024
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  17. Ten things to know about ten cardiovascular disease risk factors - 2022.American journal of preventive cardiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Carolina Ika SariHuman Neurotransmitters Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Nina EikelisHuman Neurotransmitters Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Geoffrey A HeadNeuropharmacology Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Markus SchlaichDobney Hypertension Centre, School of Medicine - Royal Perth Hospital Unit, The University of Western Australia, Perth, WA, Australia.
Peter MeikleMetabolomics Laboratories, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Gavin LambertHuman Neurotransmitters Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Elisabeth LambertHuman Neurotransmitters Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Baker Heart and Diabetes Institute · AUSwinburne University of Technology · AUUniversity of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveExcess adiposity increases the risk of type-2 diabetes and cardiovascular disease development. Beyond the simple level of adiposity, the pattern of fat distribution may influence these risks. We sought to examine if higher android fat distribution was associated with different hemodynamic, metabolic or vascular profile compared to a lower accumulation of android fat deposits in young overweight males.

methodsForty-six participants underwent dual-energy X-ray absorptiometry and were stratified into two groups. Group 1: low level of android fat (<9.5%) and group 2: high level of android fat (>9.5%). Assessments comprised measures of plasma lipid and glucose profile, blood pressure, endothelial function [reactive hyperemia index (RHI)] and muscle sympathetic nerve activity (MSNA).

resultsThere were no differences in weight, BMI, total body fat and lean mass between the two groups. Glucose tolerance and insulin resistance (fasting plasma insulin) were impaired in group 2 (

conclusionPreferential fat accumulation in the android compartment is associated with increased cardiovascular and metabolic risk via alteration of endothelial function.

Indexed as

android fatcardiovascular riskendothelial functionoverweightsympathetic activity

Identifiers

PMID31620011
PMCPMC6759693
OpenAlexW2970883411

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.