Evidence map›Paper›PMID 31623058›Full record

ArticleMolecules (Basel, Switzerland)2019

Pseudolaric Acid B Induces Growth Inhibition and Caspase-Dependent Apoptosis on Head and Neck Cancer Cell lines through Death Receptor 5.

Su-Jung Choi, Chi-Hyun Ahn, In-Hyoung Yang, Bohwan Jin, Won Woo Lee, Ji-Hoon Kim, Min-Hye Ahn, Neeti Swarup, Kyoung-Ok Hong, Ji-Ae Shin and 4 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Advances in Small Molecular Agents against Oral Cancer.Molecules (Basel, Switzerland) · 2024
    Review
  4. Article
  5. Article
  6. Molecular pathways modulated by phytochemicals in head and neck cancer.Journal of cell communication and signaling · 2023
    Review
  7. Suppressive effect of pseudolaric acid B onFrontiers in microbiology · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Su-Jung ChoiDepartment of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, Korea. anna47408@snu.ac.kr.
Chi-Hyun AhnDepartment of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, Korea. chihyun610@snu.ac.kr.
In-Hyoung YangCancer Center, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. inhyoung3@naver.com.
Bohwan JinLaboratory Animal Center, CHA University, CHA Biocomplex, Sampyeong-dong, Seongnam 13488, Korea. jnbhwan@cha.ac.kr.
Won Woo LeeLaboratory Animal Center, CHA University, CHA Biocomplex, Sampyeong-dong, Seongnam 13488, Korea. lsw232@chamc.co.kr.
Ji-Hoon KimDepartment of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, Korea. o117653266@snu.ac.kr.
Min-Hye AhnDepartment of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, Korea. mine17@snu.ac.kr.
Neeti SwarupDepartment of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, Korea. neeti@snu.ac.kr.
Kyoung-Ok HongDepartment of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, Korea. hongko95@snu.ac.kr.
Ji-Ae ShinDepartment of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, Korea. sky21sm@snu.ac.kr.
Nam-Tae WooDepartment of ChemBio Specialization Program (CK-II), Dankook University, Cheonan 31116, Korea. natwoo2@gmail.com.
Seong Doo HongDepartment of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, Korea. hongsd@snu.ac.kr.
Jae-Il LeeDepartment of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, Korea. jilee@snu.ac.kr.
Sung-Dae ChoDepartment of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, Korea. efiwdsc@snu.ac.kr.ORCID 0000-0001-8670-9579
Seoul National University · KRCHA University · KRDankook University · KRTexas Tech University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudolaric Acid B (PAB), diterpenoid isolated from the root bark of

Indexed as

AnimalsApoptosisCell Line, TumorCell ProliferationCell SurvivalDisease Models, AnimalDiterpenesDrugs, Chinese HerbalHead and Neck NeoplasmsHumansMiceMolecular StructureReceptors, TNF-Related Apoptosis-Inducing LigandXenograft Model Antitumor AssaysDiterpenesDrugs, Chinese Herbalpseudolaric acid BReceptors, TNF-Related Apoptosis-Inducing LigandTNFRSF10B protein, humancaspase-8 Apoptosisdeath receptor 5oral cancerpseudolaric acid B

Identifiers

PMID31623058
PMCPMC6832876
OpenAlexW2980510112

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.