Evidence map›Paper›PMID 31647879›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Endothelial cell-specific redox gene modulation inhibits angiogenesis but promotes B16F0 tumor growth in mice.

Yoshimitsu Yura, Brian S H Chong, Ryan D Johnson, Yosuke Watanabe, Yuko Tsukahara, Beatriz Ferran, Colin E Murdoch, Jessica B Behring, Mark E McComb, Catherine E Costello and 4 more

Open access · greenAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. A Prognostic Activity of Glutaredoxin 1 Protein (Grx1) in Colon Cancer.International journal of molecular sciences · 2024
    Article
  3. Article
  4. Review
  5. Hypoxia-dependent drivers of melanoma progression.Journal of experimental & clinical cancer research : CR · 2021
    Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Yoshimitsu YuraDepartment of Medicine, Vascular Biology Section, Whitaker Cardiovascular Institute, Boston, Massachusetts, USA.
Brian S H ChongDepartment of Medicine, Vascular Biology Section, Whitaker Cardiovascular Institute, Boston, Massachusetts, USA.
Ryan D JohnsonDepartment of Medicine, Vascular Biology Section, Whitaker Cardiovascular Institute, Boston, Massachusetts, USA.
Yosuke WatanabeDepartment of Medicine, Vascular Biology Section, Whitaker Cardiovascular Institute, Boston, Massachusetts, USA.
Yuko TsukaharaDepartment of Medicine, Vascular Biology Section, Whitaker Cardiovascular Institute, Boston, Massachusetts, USA.
Beatriz FerranDepartment of Medicine, Vascular Biology Section, Whitaker Cardiovascular Institute, Boston, Massachusetts, USA.
Colin E MurdochDepartment of Medicine, Vascular Biology Section, Whitaker Cardiovascular Institute, Boston, Massachusetts, USA.
Jessica B BehringDepartment of Medicine, Vascular Biology Section, Whitaker Cardiovascular Institute, Boston, Massachusetts, USA.
Mark E McCombCardiovascular Proteomics Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Catherine E CostelloCardiovascular Proteomics Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Yvonne M W Janssen-HeiningerDepartment of Pathology and Laboratory Medicine, University of Vermont, Burlington, Vermont, USA.
Richard A CohenDepartment of Medicine, Vascular Biology Section, Whitaker Cardiovascular Institute, Boston, Massachusetts, USA.
Markus M BachschmidDepartment of Medicine, Vascular Biology Section, Whitaker Cardiovascular Institute, Boston, Massachusetts, USA.
Reiko MatsuiDepartment of Medicine, Vascular Biology Section, Whitaker Cardiovascular Institute, Boston, Massachusetts, USA.
University of Vermont · USUniversity of Virginia · USBoston University · USCenter for Vascular Biology Research · US

Funding

Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
Multidisciplinary Training in Cardiovascular ResearchT32HL007224 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HAMBURG, NAOMI MIRIAM, WAINFORD, RICHARD DAVID · 1985 to 2020
$12.3M
S-glutathionylation chemistry in fibrotic lung remodelingR35HL135828 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI JANSSEN-HEININGER, YVONNE M. W. · 2017 to 2023
$6.5M
Redox Regulation of p21ras in AngiogenesisR37HL104017 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI COHEN, RICHARD A · 2010 to 2014
$2.2M
S-glutathionylation chemistry, glycolysis and obese allergic asthmaR01HL137268 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI DIXON, ANNE E, VAN DER VLIET, ALBERT · 2017 to 2020
$2.1M
Redox Control of Hepatic Lipid MetabolismR01DK103750 · NIDDK · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BACHSCHMID, MARKUS MICHAEL · 2015 to 2019
$1.8M
Regulation of ischemic limb vascularization by glutaredoxin-1R01HL133013 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MATSUI, REIKO · 2016 to 2019
$1.6M
Regulation of ischemic vascularization by glutaredoxin-1 by agingR03AG051857 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MATSUI, REIKO · 2016 to 2017
$236k
NCATS NIH HHS UL1 TR001430NHLBI NIH HHS HHSN268201000031CNHLBI NIH HHS R01 HL133013NHLBI NIH HHS R01 HL137268NHLBI NIH HHS R35 HL135828NHLBI NIH HHS R37 HL104017NHLBI NIH HHS T32 HL007224NIA NIH HHS R03 AG051857NIDDK NIH HHS R01 DK103750
6 · The paper itself

Abstract

Glutaredoxin-1 (Glrx) is a small cytosolic enzyme that removes

Indexed as

AnimalsEndothelial CellsFemaleFemoral ArteryGlutaredoxinsHindlimbIschemiaLigationMaleMelanomaMiceMice, TransgenicNeoplasms, ExperimentalNeovascularization, PathologicNeovascularization, PhysiologicGlrx protein, mouseGlutaredoxinsglutaredoxinmelanomaS-glutathionylationvascularvasculogenic mimicry

Identifiers

PMID31647879
PMCPMC6894059
OpenAlexW2981920802

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.