Evidence map›Paper›PMID 31649630›Full record

ArticleFrontiers in microbiology2019

Association of TREM-1, IL-1β, IL-33/ST2, and TLR Expressions With the Pathogenesis of Ocular Toxoplasmosis in Mouse Models on Different Genetic Backgrounds.

Yanxia Zhang, Jian He, Huanqin Zheng, Shiguang Huang, Fangli Lu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Dynamic Immune Profile in French Toxoplasmosis Patients.The Journal of infectious diseases · 2022
    Article
  8. Frontiers in cellular and infection microbiology · 2022
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yanxia ZhangDepartment of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Jian HeDepartment of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Huanqin ZhengDepartment of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Shiguang HuangSchool of Stomatology, Jinan University, Guangzhou, China.
Fangli LuDepartment of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Sun Yat-sen University · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ocular toxoplasmosis (OT) is one of the most common causes of posterior uveitis. The signaling of triggering receptor expressed on myeloid cells (TREM)-1 amplifies inflammation, whereas TREM-2 signaling is anti-inflammatory. IL-1β is a major driver of inflammation during infection. Toll-like receptors (TLRs) play important roles in protective immune response during

Indexed as

BALB/c miceC57BL/6 miceIL-1βIL-33/ST2neutrophilsocular toxoplasmosisTLRsTREM-1

Identifiers

PMID31649630
PMCPMC6794992
OpenAlexW2979889616

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.