Evidence map›Paper›PMID 31650902›Full record

ArticleThyroid : official journal of the American Thyroid Association2020

Class III PI3K Vps34 Controls Thyroid Hormone Production by Regulating Thyroglobulin Iodination, Lysosomal Proteolysis, and Tissue Homeostasis.

Giuseppina Grieco, Tongsong Wang, Ophélie Delcorte, Catherine Spourquet, Virginie Janssens, Aurélie Strickaert, Héloïse P Gaide Chevronnay, Xiao-Hui Liao, Benoît Bilanges, Samuel Refetoff and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Class III PI3K Biology.Current topics in microbiology and immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Giuseppina GriecoCell Biology Unit, de Duve Institute and Université Catholique de Louvain, Brussels, Belgium.
Tongsong WangCell Biology Unit, de Duve Institute and Université Catholique de Louvain, Brussels, Belgium.
Ophélie DelcorteCell Biology Unit, de Duve Institute and Université Catholique de Louvain, Brussels, Belgium.
Catherine SpourquetCell Biology Unit, de Duve Institute and Université Catholique de Louvain, Brussels, Belgium.
Virginie JanssensCell Biology Unit, de Duve Institute and Université Catholique de Louvain, Brussels, Belgium.
Aurélie StrickaertThyroid Cancer Group, Faculty of Medecine, Institute of Interdisciplinary Research (IRIBHM), Université libre de Bruxelles, Brussels, Belgium.
Héloïse P Gaide ChevronnayCell Biology Unit, de Duve Institute and Université Catholique de Louvain, Brussels, Belgium.
Xiao-Hui LiaoDepartment of Medicine, The University of Chicago, Chicago, Illinois.
Benoît BilangesCell Signalling, UCL Cancer Institute, University College London, London, United Kingdom.
Samuel RefetoffDepartment of Medicine, The University of Chicago, Chicago, Illinois.
Bart VanhaesebroeckCell Signalling, UCL Cancer Institute, University College London, London, United Kingdom.
Carine MaenhautThyroid Cancer Group, Faculty of Medecine, Institute of Interdisciplinary Research (IRIBHM), Université libre de Bruxelles, Brussels, Belgium.
Pierre J CourtoyCell Biology Unit, de Duve Institute and Université Catholique de Louvain, Brussels, Belgium.
Christophe E PierreuxCell Biology Unit, de Duve Institute and Université Catholique de Louvain, Brussels, Belgium.
de Duve Institute · BECRUK Lung Cancer Centre of Excellence · GBUniversité Libre de Bruxelles · BEUniversity of Chicago · US

Funding

THYROID PHYSIOLOGY STUDIES OF INHERITED DISORDERSR01DK015070 · NIDDK · UNIVERSITY OF CHICAGO · PI ANTONIO C BIANCO, Alexandra Mihaela Dumitrescu · 1986 to 2026
$8.1M
Medical Research Council G0700755NIDDK NIH HHS R01 DK015070
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsClass III Phosphatidylinositol 3-KinasesHydrogen PeroxideLysosomesMiceProteolysisSodium-Iodide SymportersSymportersThyroglobulinThyroid Epithelial CellsThyroid GlandThyroid HormonesClass III Phosphatidylinositol 3-KinasesHydrogen PeroxideSodium-Iodide SymportersSymportersThyroglobulinThyroid HormonesautophagyhormoneorganificationthyroidVps34

Identifiers

PMID31650902
PMCPMC6983755
OpenAlexW2982276386

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.