Evidence map›Paper›PMID 31656501›Full record

ArticleAfrican health sciences2019

Association of Vitamin D receptor gene

Hussain Fatma, Sattar Naila Abdul

Open access · diamondAbstract read
In one paragraph

Article in African health sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Association of VDR gene ApaI polymorphism with obesity in Iranian population.Biomedica : revista del Instituto Nacional de Salud · 2021
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Hussain FatmaDepartment of Biochemistry, Faculty of Sciences, University of Agriculture, Faisalabad, Pakistan. fatmauaf@yahoo.com.
Sattar Naila AbdulDepartment of Biochemistry, Government College for Women University, Faisalabad, Pakistan. uaf_naila_sattar@yahoo.com.
Government College Women University Faisalabad · PKUniversity of Faisalabad · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundType 2 diabetes mellitus (T2DM) is a complex metabolic disorder with strong genetic components. The reported association of vitamin D receptor (VDR) gene polymorphisms varies among ethnic groups.

objectivesThe present study was conducted to determine association of vitamin D receptor gene

methodsBlood samples were collected from 150 T2DM patients and 100 non-diabetic engaged by convenient sampling method. After collection of demographic data, assessment of fasting glucose (FG), vitamin D, HbA1c, renal function tests, liver function tests and lipid profile was done. Candidate gene polymorphism was analyzed by DNA amplification with polymerase chain reaction and endonuclease digestion.

resultsBiochemical parameters were significantly different among case and control groups. Associations of

conclusionThe current study did not provide evidence for the association of VDR gene

Indexed as

Polymorphism, Single NucleotideDiabetes Mellitus, Type 2FemaleGenetic Predisposition to DiseaseGenotypeHumansMaleMiddle AgedPakistanReceptors, CalcitriolReceptors, CalcitriolVDR protein, humansingle nucleotide polymorphismtype 2 diabetes mellitusVitamin D receptor gene

Identifiers

PMID31656501
PMCPMC6794500
OpenAlexW2969323552

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.