Evidence map›Paper›PMID 31659517›Full record

ArticleEJNMMI radiopharmacy and chemistry2019

Automated synthesis of [

Prashanth K Padakanti, Shihong Li, Alexander Schmitz, David Mankoff, Robert H Mach, Hsiaoju S Lee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI radiopharmacy and chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. l-[5-Acta pharmaceutica Sinica. B · 2025
    Article
  3. Review
  4. First-in-Human PET Imaging and Estimated Radiation Dosimetry of l-[5-Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  5. Review
  6. L-5-[Nuclear medicine and biology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Prashanth K PadakantiDepartment of Radiology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Shihong LiDepartment of Radiology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Alexander SchmitzDepartment of Radiology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
David MankoffDepartment of Radiology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Robert H MachDepartment of Radiology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Hsiaoju S LeeDepartment of Radiology, University of Pennsylvania, Philadelphia, PA, 19104, USA. leehsi@pennmedicine.upenn.edu.
University of Pennsylvania · US

Funding

Molecular Imaging Markers for Glutaminolysis in Breast CancerR01CA211337 · NCI · UNIVERSITY OF PENNSYLVANIA · PI MANKOFF, DAVID A., ZHOU, RONG · 2017 to 2021
$2.0M
Department of Energy DE-SE0012476NCI NIH HHS R01 CA211337NIH HHS NIH/NCI R01-CA211337Susan G. Komen SAC130060
6 · The paper itself

Abstract

backgroundL-Glutamine (L-Gln) is the most abundant amino acid present in the human body and is involved in numerous metabolic pathways. Glutaminolysis is the metabolic process deployed by many aggressive cancers such as triple negative breast cancer (TNBC). Imaging the metabolic pathways of L-glutamine could provide more insights into tumor biology. Reliable and reproducible automated synthesis of [

results[

conclusionsAll the steps including drying of the mixture of base and crown ether, preparation of [

Indexed as

[11C]L-glutamineRadiochemical synthesisSynthra HCN plus module and HPLC

Identifiers

PMID31659517
PMCPMC6426911
OpenAlexW2936700930

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.