Evidence map›Paper›PMID 31666356›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Audiogenic Seizures in the

Darya Gonzalez, Madison Tomasek, Seth Hays, Vinay Sridhar, Simon Ammanuel, Chia-Wei Chang, Karen Pawlowski, Kimberly M Huber, Jay R Gibson

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. bioRxiv : the preprint server for biology · 2026
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  5. Pharmacologic MRI Brain Imaging Studies of Serotonin 5-HTPharmacology research & perspectives · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Altered Auditory Maturation in Fragile X Syndrome and Its Involvement in Audiogenic Seizure Susceptibility.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Hyper-extralemniscal model of Fragile X syndrome.Cerebral cortex (New York, N.Y. : 1991) · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Darya GonzalezDepartment of Neuroscience, Dallas, and.
Madison TomasekDepartment of Neuroscience, Dallas, and.
Seth HaysDepartment of Neuroscience, Dallas, and.ORCID 0000-0003-4225-241X
Vinay SridharDepartment of Neuroscience, Dallas, and.
Simon AmmanuelDepartment of Neuroscience, Dallas, and.ORCID 0000-0003-2290-2892
Chia-Wei ChangDepartment of Neuroscience, Dallas, and.
Karen PawlowskiDepartment of Otolaryngology and Biomedical Engineering Program, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9035.ORCID 0000-0002-1947-6725
Kimberly M HuberDepartment of Neuroscience, Dallas, and Jay.Gibson@UTSouthwestern.edu Kimberly.Huber@UTSouthwestern.edu.
Jay R GibsonDepartment of Neuroscience, Dallas, and Jay.Gibson@UTSouthwestern.edu Kimberly.Huber@UTSouthwestern.edu.
Society for Neuroscience · USSouthwestern Medical Center · USThe University of Texas Southwestern Medical Center · US

Funding

Neurophysiological and acute pharmacological studies in FXS patientsU54HD082008 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI HUBER, KIMBERLY M. · 2014 to 2019
$9.8M
NICHD NIH HHS U54 HD082008
6 · The paper itself

Abstract

Fragile X syndrome (FXS) is the most common form of inherited intellectual disability and the leading monogenetic cause of autism. One symptom of FXS and autism is sensory hypersensitivity (also called sensory over-responsivity). Perhaps related to this, the audiogenic seizure (AGS) is arguably the most robust behavioral phenotype in the FXS mouse model-the

Indexed as

AnimalsEpilepsy, ReflexFragile X Messenger Ribonucleoprotein 1Fragile X SyndromeGene Expression RegulationInferior ColliculiMaleMiceMice, KnockoutNeuronsOrgan of CortiVesicular Glutamate Transport Protein 2Fmr1 protein, mouseFragile X Messenger Ribonucleoprotein 1Slc17a6 protein, mouseVesicular Glutamate Transport Protein 2auditoryFmr1fragile Xhypersensitivitymouseseizure

Identifiers

PMID31666356
PMCPMC6891051
OpenAlexW2982612889

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.