← Statins × adverse events & safety

SynthesisLipids in health and disease2019

Association of statin use and clinical outcomes in heart failure patients: a systematic review and meta-analysis.

Agata Bielecka-Dabrowa et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedas reported · 88,100 people · 2019

Not counted

Reduced deaths

−23%−28% to −17%

Bigger than 7 in 10 for all-cause mortality

As reported

HR 0.77, 95% CI 0.72–0.83 · the paper's word: All-cause mortality

Not counted

Reduced deaths

−23%−28% to −17%

Bigger than 7 in 10 for all-cause mortality

As reported

HR 0.77, 95% CI 0.72–0.83 · the paper's word: All-cause mortality

Not counted

Lowered adverse events & safety

−20%−36% to −1%

Bigger than 5 in 10 for adverse events & safety

As reported

HR 0.80, 95% CI 0.64–0.99

Three numbers in the abstract

the abstract, start to end

… lower risk of all-cause mortality (HR 0.77, 95% confidence interval [CI], …

… a lower risk of all-cause mortality (HR 0.77, 95% confidence interval [CI], …

… in statin users in both EF groups (HR 0.80 95CI: 0.64-0.99, p = 0.04, and …

← favours treatmentfavours comparator →
could be chance
All-cause mortality
HR 0.770.72–0.83
All-cause mortality
HR 0.770.72–0.83
Adverse events & safety
HR 0.800.64–0.99
StatinsAll-cause mortalityAdverse events & safety
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Full record →Abstract, authors, funding and every citing paper · PMID 31672151