Evidence map›Paper›PMID 31673922›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020

Correlation between disease severity factors and EQ-5D utilities in chronic obstructive pulmonary disease.

Cristina Esquinas, Maria A Ramon, Alexa Nuñez, Jesús Molina, José A Quintano, Miguel Roman-Rodríguez, Karlos Naberan, Carl Llor, Carlos Roncero, Marc Miravitlles and 1 more

Open access · greenAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Testing the psychometric characteristics of EQ-5D-5L and respiratory bolt-ons using a sample of the Australian population.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  4. Article
  5. Associations between the EQ-5D-5L and exacerbations of chronic obstructive pulmonary disease in the ETHOS trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  6. Value of Information Analysis of a Web-Based Self-Management Intervention for Chronic Obstructive Pulmonary Disease.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Burden of Disease Among Exacerbating Patients with COPD Treated with Triple Therapy in Spain.International journal of chronic obstructive pulmonary disease · 2021
    Observational
  12. Article
  13. Article
  14. Relationship Between Clinical Control, Respiratory Symptoms and Quality of Life for Patients with COPD.International journal of chronic obstructive pulmonary disease · 2020
    Observational
  15. The Experience of COPD Patients in Lockdown Due to the COVID-19 Pandemic.International journal of chronic obstructive pulmonary disease · 2020
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Cristina EsquinasDepartment of Pneumology, Hospital Universitari Vall d'Hebron, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain. crise4@hotmail.com.
Maria A RamonDepartment of Pneumology, Hospital Universitari Vall d'Hebron, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain.
Alexa NuñezDepartment of Pneumology, Hospital Universitari Vall d'Hebron, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain.
Jesús MolinaDirección Asistencial Oeste, Centro de Salud Francia, Madrid, Spain.
José A QuintanoCentro de Salud Lucena, Córdoba, Spain.
Miguel Roman-RodríguezPrimary Health Care Center Son Pisà, IB-Salut, Palma de Mallorca, Spain.
Karlos NaberanCentro de Salud Fuentes de Ebro, Saragossa, Spain.
Carl LlorPrimary Care Centre Via Roma, Barcelona, Spain.
Carlos RonceroPsychiatric Service, University of Salamanca Health Care Complex, Institute of Biomedicine of Salamanca, University of Salamanca, Salamanca, Spain.
Marc MiravitllesDepartment of Pneumology, Hospital Universitari Vall d'Hebron, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain.
Miriam BarrechegurenDepartment of Pneumology, Hospital Universitari Vall d'Hebron, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain.
Vall d'Hebron Hospital Universitari · ESCentro de Investigación Biomédica en Red de Enfermedades Respiratorias · ESServei de Salut de les Illes Balears · ESUniversidad de Salamanca · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeImpaired health-related quality of life (HRQoL) is associated with poor health outcomes in chronic obstructive pulmonary disease (COPD). The aim of this study was to determine health utilities in patients with COPD and to identify the variables with the greatest impact.

methodsThis is a pooled analysis of data from 4 observational studies performed in stable COPD patients. Evaluation of patient HRQoL utilities was performed using the Spanish version of the self-administered EuroQoL 5 Dimensions (EQ-5D) questionnaire. EQ-5D utilities were described and compared according to several markers of disease severity.

results6198 patients reported a mean (SD) EQ-5D index of 0.67 (0.26). A linear dose response relationship between EQ-5D utility and modified Medical Research Council (mMRC) score, forced expiratory volume in one 1 s (% predicted), COPD hospital admissions in the previous year, self-reported daily walking time, Charlson index, body mass index, obstruction, dyspnoea and exacerbation (BODEx) index, COPD assessment test (CAT), hospital anxiety and depression scale was observed (p for trend < 0.001). In multivariate analysis, patients reporting lower utility values were those with more dyspnoea, more comorbidities, using long-term oxygen therapy, with previous hospitalisations due to a COPD exacerbation and higher (worse) CAT score.

conclusionHRQoL measures such as EQ-5D can assist clinicians to understand the impact of respiratory disease on COPD patients.

Indexed as

AgedCross-Sectional StudiesFemaleHumansMalePulmonary Disease, Chronic ObstructiveQuality of LifeCATCOPDEQ-5DHealth-Related Quality of Life

Identifiers

PMID31673922
OpenAlexW2988564120

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.