Evidence map›Paper›PMID 31682586›Full record

Trial reportJMIR mHealth and uHealth2019

Development of a Deep Learning Model for Dynamic Forecasting of Blood Glucose Level for Type 2 Diabetes Mellitus: Secondary Analysis of a Randomized Controlled Trial.

Syed Hasib Akhter Faruqui, Yan Du, Rajitha Meka, Adel Alaeddini, Chengdong Li, Sara Shirinkam, Jing Wang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in JMIR mHealth and uHealth, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Syed Hasib Akhter FaruquiDepartment of Mechanical Engineering, University of Texas at San Antonio, San Antonio, TX, United States.ORCID 0000-0002-5073-8690
Yan DuCenter on Smart and Connected Health Technologies, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.ORCID 0000-0003-0683-3989
Rajitha MekaDepartment of Mechanical Engineering, University of Texas at San Antonio, San Antonio, TX, United States.ORCID 0000-0002-2622-8412
Adel AlaeddiniDepartment of Mechanical Engineering, University of Texas at San Antonio, San Antonio, TX, United States.ORCID 0000-0003-4451-3150
Chengdong LiCenter on Smart and Connected Health Technologies, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.ORCID 0000-0001-5330-9624
Sara ShirinkamDepartment of Mathematics and Statistics, University of the Incarnate Word, San Antonio, TX, United States.ORCID 0000-0002-8153-4754
Jing WangCenter on Smart and Connected Health Technologies, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.ORCID 0000-0002-4012-0977

Funding

NRSA Training Core (TL1)TL1TR002647 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHUN, YONG-HEE PATRICIA, FREI, CHRISTOPHER R. · 2018 to 2022
$1.8M
A Novel Probabilistic Methodology for Prediction of Emerging Diseases in Patients with Multiple Chronic ConditionsSC2GM118266 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI ALAEDDINI, ADEL · 2016 to 2018
$441k
NCATS NIH HHS TL1 TR002647NIGMS NIH HHS SC2 GM118266
6 · The paper itself

Abstract

backgroundType 2 diabetes mellitus (T2DM) is a major public health burden. Self-management of diabetes including maintaining a healthy lifestyle is essential for glycemic control and to prevent diabetes complications. Mobile-based health data can play an important role in the forecasting of blood glucose levels for lifestyle management and control of T2DM.

objectiveThe objective of this work was to dynamically forecast daily glucose levels in patients with T2DM based on their daily mobile health lifestyle data including diet, physical activity, weight, and glucose level from the day before.

methodsWe used data from 10 T2DM patients who were overweight or obese in a behavioral lifestyle intervention using mobile tools for daily monitoring of diet, physical activity, weight, and blood glucose over 6 months. We developed a deep learning model based on long short-term memory-based recurrent neural networks to forecast the next-day glucose levels in individual patients. The neural network used several layers of computational nodes to model how mobile health data (food intake including consumed calories, fat, and carbohydrates; exercise; and weight) were progressing from one day to another from noisy data.

resultsThe model was validated based on a data set of 10 patients who had been monitored daily for over 6 months. The proposed deep learning model demonstrated considerable accuracy in predicting the next day glucose level based on Clark Error Grid and ±10% range of the actual values.

conclusionsUsing machine learning methodologies may leverage mobile health lifestyle data to develop effective individualized prediction plans for T2DM management. However, predicting future glucose levels is challenging as glucose level is determined by multiple factors. Future study with more rigorous study design is warranted to better predict future glucose levels for T2DM management.

Indexed as

Blood GlucoseDeep LearningDiabetes Mellitus, Type 2FemaleForecastingHumansMaleMiddle AgedPilot ProjectsPredictive Value of TestsSelf-ManagementBlood Glucoseglucose level predictionlong short-term memory (LSTM)-based recurrent neural networks (RNNs)mobile health lifestyle datatype 2 diabetes

Identifiers

PMID31682586
PMCPMC6858613

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.