Evidence map›Paper›PMID 31690628›Full record

ArticleThe Journal of biological chemistry2019

Phosphorylation of the Gα protein Gpa2 promotes protein kinase A signaling in yeast.

Shan Huang, Alex Benben, Robert Green, Nina Cheranda, Grace Lee, Benita Joseph, Shannon Keaveney, Yuqi Wang

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Shan HuangDepartment of Biology, Saint Louis University, St. Louis, Missouri 63103.
Alex BenbenDepartment of Biology, Saint Louis University, St. Louis, Missouri 63103.
Robert GreenDepartment of Biology, Saint Louis University, St. Louis, Missouri 63103.
Nina CherandaDepartment of Biology, Saint Louis University, St. Louis, Missouri 63103.
Grace LeeDepartment of Biology, Saint Louis University, St. Louis, Missouri 63103.
Benita JosephDepartment of Biology, Saint Louis University, St. Louis, Missouri 63103.
Shannon KeaveneyDepartment of Biology, Saint Louis University, St. Louis, Missouri 63103.
Yuqi WangDepartment of Biology, Saint Louis University, St. Louis, Missouri 63103. Electronic address: yuqi.wang@slu.edu.
Saint Louis University · USSaint Louis University · ES

Funding

Novel Function and Regulation of G alpha ProteinR15GM128047 · NIGMS · SAINT LOUIS UNIVERSITY · PI WANG, YUQI · 2018 to 2018
$303k
NIGMS NIH HHS R15 GM128047
6 · The paper itself

Abstract

Heterotrimeric G proteins are important molecular switches that facilitate transmission of a variety of signals from the outside to the inside of cells. G proteins are highly conserved, enabling study of their regulatory mechanisms in model organisms such as the budding yeast

Indexed as

Cell MembraneCyclic AMP-Dependent Protein KinasesGene Expression Regulation, FungalGlycogen Synthase KinasesGTP-Binding Protein alpha SubunitsPhosphorylationSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionCyclic AMP-Dependent Protein KinasesGlycogen Synthase KinasesGpa2 protein, S cerevisiaeGTP-Binding Protein alpha SubunitsSaccharomyces cerevisiae Proteinscellular localizationglycogen synthase kinaseGpa2G proteinnutrient signalingPKAposttranslational modification (PTM)protein kinaseprotein phosphorylationsporulationyeast

Identifiers

PMID31690628
PMCPMC6901295
OpenAlexW2986118134

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.