Evidence map›Paper›PMID 31696865›Full record

ReviewMedical science monitor : international medical journal of experimental and clinical research2019

Increased Levels of Glycated Hemoglobin A1c and Iron Deficiency Anemia: A Review.

Wenjia Guo, Qi Zhou, Yanan Jia, Jiancheng Xu

Abstract readReview
In one paragraph

Review in Medical science monitor : international medical journal of experimental and clinical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  13. The role of HbA1c in identifying dogs at high risk for diabetes despite normal blood glucose levels.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wenjia GuoDepartment of Laboratory Medicine, First Hospital of Jilin University, Changchun, Jilin, China (mainland).
Qi ZhouDepartment of Pediatrics, First Hospital of Jilin University, Changchun, Jilin, China (mainland).
Yanan JiaDepartment of Laboratory Medicine, First Hospital of Jilin University, Changchun, Jilin, China (mainland).
Jiancheng XuDepartment of Laboratory Medicine, First Hospital of Jilin University, Changchun, Jilin, China (mainland).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Worldwide, the prevalence of diabetes remains high. Studies have shown that iron deficiency anemia (IDA) is associated with increased levels of glycated hemoglobin A1c (HbA1c), but the mechanism remains unclear. Hematological changes, iron metabolism, study methodology, and other factors could affect the results of diagnostic investigations, leading to false results. Red blood cell turnover in the bone marrow and the quality and heterogeneity of erythrocytes may influence the rate of hemoglobin glycation. By changing the structure of hemoglobin and inducing peroxidation, iron deficiency accelerates glycation. This review aims to discuss the possible causes of the association between increased levels of HbA1c and IDA.

Indexed as

AnemiaAnemia, Iron-DeficiencyBlood GlucoseDiabetes MellitusErythrocytesFemaleGlycated HemoglobinHemoglobinsHumansIronMalePrevalenceBlood GlucoseGlycated HemoglobinHemoglobinsIron

Identifiers

PMID31696865
PMCPMC6857442

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.