Evidence map›Paper›PMID 31699684›Full record

ArticleBiology open2019

Muc5b-deficient mice develop early histological lung abnormalities.

Hélène Valque, Valérie Gouyer, Catherine Duez, Christophe Leboeuf, Philippe Marquillies, Marc Le Bert, Ségolène Plet, Bernhard Ryffel, Anne Janin, Frédéric Gottrand and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Normalization of Muc5b ameliorates airway mucus plugging during persistentAmerican journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. The Known Unknowns of the Immune Response toJournal of fungi (Basel, Switzerland) · 2021
    Review
  11. The Cervicovaginal Mucus Barrier.International journal of molecular sciences · 2020
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Hélène ValqueLIRIC UMR 995; Univ. Lille; Inserm; CHU Lille, F-59045 Lille, France.
Valérie GouyerLIRIC UMR 995; Univ. Lille; Inserm; CHU Lille, F-59045 Lille, France.ORCID http://orcid.org/0000-0002-4223-7060
Catherine DuezCIIL Inserm U1019; CNRS UMR 8204; Institut Pasteur de Lille; Univ. Lille, F-59019 Lille, France.ORCID http://orcid.org/0000-0002-2327-1095
Christophe LeboeufInserm UMR_S 1165; Université Paris- Diderot, Institut Universitaire d'Hématologie, AP-HP-Hôpital Saint Louis, F-75010 Paris, France.ORCID http://orcid.org/0000-0002-6537-0550
Philippe MarquilliesCIIL Inserm U1019; CNRS UMR 8204; Institut Pasteur de Lille; Univ. Lille, F-59019 Lille, France.
Marc Le BertCNRS UMR 7355, University of Orleans, Laboratory of Experimental and Molecular Immunology and Neurogenetics (INEM), F-45071 Orleans, France.
Ségolène PletLIRIC UMR 995; Univ. Lille; Inserm; CHU Lille, F-59045 Lille, France.
Bernhard RyffelCNRS UMR 7355, University of Orleans, Laboratory of Experimental and Molecular Immunology and Neurogenetics (INEM), F-45071 Orleans, France.ORCID http://orcid.org/0000-0003-2897-8230
Anne JaninInserm UMR_S 1165; Université Paris- Diderot, Institut Universitaire d'Hématologie, AP-HP-Hôpital Saint Louis, F-75010 Paris, France.ORCID http://orcid.org/0000-0002-9595-6261
Frédéric GottrandLIRIC UMR 995; Univ. Lille; Inserm; CHU Lille, F-59045 Lille, France.ORCID http://orcid.org/0000-0002-5290-0436
Jean-Luc DesseynLIRIC UMR 995; Univ. Lille; Inserm; CHU Lille, F-59045 Lille, France jean-luc.desseyn@inserm.fr.ORCID http://orcid.org/0000-0001-6876-8049
Inserm · FRCentre National de la Recherche Scientifique · FRUniversité d'Orléans · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gel-forming mucins are the main organic component responsible for physical properties of the mucus hydrogels. While numerous biological functions of these mucins are well documented, specific physiological functions of each mucin are largely unknown. To investigate

Indexed as

Gel-forming mucinKnockoutRespiratory distressYoung mice

Identifiers

PMID31699684
PMCPMC6899002
OpenAlexW2983646570

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.