ArticleAnnals of translational medicine2019
Total bilirubin is negatively related to diabetes mellitus in Chinese elderly: a community study.
Article in Annals of translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
- Association of Serum Bilirubin Levels with Macro- and Microvascular Complications in Chinese People with Type 2 Diabetes Mellitus: New Insight on Gender Differences.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Long-Term Effects of Biliverdin Reductase a Deficiency inAntioxidants (Basel, Switzerland) · 2021Article
- Relationship between serum bilirubin concentration and sarcopenia in patients with type 2 diabetes: a cross-sectional study.The Journal of international medical research · 2021Article
- Serum bilirubin and ischaemic stroke: a review of literature.Stroke and vascular neurology · 2020Review
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
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Abstract
backgroundSerum total bilirubin (TB) was used as a predictor of diabetes mellitus (DM) and this study was undertaken to investigate the relationship between serum TB and DM.
methodsIn this cross-sectional study, a total of 3,867 subjects older than 65 years were recruited from East China. The anthropometric data, lifestyle and past history were collected. The fasting blood glucose, total cholesterol (TC), triglycerides (TGs), TB and alanine aminotransferase (ALT) were detected. The prevalence of DM was calculated for every serum TB quartile. Logistic regression analysis was employed to evaluate the relationship between serum TB and DM.
resultsSerum TB was significantly higher in non-DM than DM patients (P=0.001). Serum TB was negatively related to the prevalence of DM (P=0.004). Logistic regression analysis revealed that serum TB was an independent prognostic factor of DM [odds ratio (OR): 0.876, 95% confidence interval (CI): 0.807-0.951].
conclusionsOur results showed serum TB in physiological range is an independent risk factor of DM in old people; the prevalence of DM in old people has a linear relationship with serum TB quartiles; the prevalence of DM reduces with the increasing of serum TB within physiological range.
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