Evidence mapPaperPMID 31703271Full record

SynthesisInternational journal of molecular sciences2019

Omega-3 Polyunsaturated Fatty Acids and Stroke Burden.

Yuji Ueno, Nobukazu Miyamoto, Kazuo Yamashiro, Ryota Tanaka, Nobutaka Hattori

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Free Fatty Acids Are Associated with the Cognitive Functions in Stroke Survivors.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yuji UenoDepartment of Neurology, Juntendo University Faculty of Medicine, Tokyo 113-8421, Japan.ORCID 0000-0002-8617-3695
Nobukazu MiyamotoDepartment of Neurology, Juntendo University Faculty of Medicine, Tokyo 113-8421, Japan.
Kazuo YamashiroDepartment of Neurology, Juntendo University Faculty of Medicine, Tokyo 113-8421, Japan.
Ryota TanakaStroke Center and Division of Neurology, Department of Medicine, Jichi Medical University, Tochigi 329-0498, Japan.
Nobutaka HattoriDepartment of Neurology, Juntendo University Faculty of Medicine, Tokyo 113-8421, Japan.ORCID 0000-0002-2034-2556
Juntendo University · JPJichi Medical University · JP

Funding

Japan Society for the Promotion of Science JP17K09764Ministry of Education, Culture, Sports, Science and Technology S1411066Takeda Science Foundation 2018
6 · The paper itself

Abstract

Stroke is a major leading cause of death and disability worldwide. N-3 polyunsaturated fatty acids (PUFAs) including eicosapentaenoic acid and docosahexaenoic acid have potent anti-inflammatory effects, reduce platelet aggregation, and regress atherosclerotic plaques. Since the discovery that the Greenland Eskimo population, whose diet is high in marine n-3 PUFAs, have a lower incidence of coronary heart disease than Western populations, numerous epidemiological studies to explore the associations of dietary intakes of fish and n-3 PUFAs with cardiovascular diseases, and large-scale clinical trials to identify the benefits of treatment with n-3 PUFAs have been conducted. In most of these studies the incidence and mortality of stroke were also evaluated mainly as secondary endpoints. Thus, a systematic literature review regarding the association of dietary intake of n-3 PUFAs with stroke in the epidemiological studies and the treatment effects of n-3 PUFAs in the clinical trials was conducted. Moreover, recent experimental studies were also reviewed to explore the molecular mechanisms of the neuroprotective effects of n-3 PUFAs after stroke.

Indexed as

Cost of IllnessFatty Acids, Omega-3HumansIncidenceStrokeUnited StatesFatty Acids, Omega-3docosahexaenoic acideicosapentaenoic acidomega-3 PUFAstroke

Identifiers

PMID31703271
PMCPMC6888676
OpenAlexW2985145736

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.