Evidence map›Paper›PMID 31703601›Full record

ArticleBMC veterinary research2019

Lipid and metabolic profiles in female dogs with mammary carcinoma receiving dietary fish oil supplementation.

Keidylania Costa-Santos, Karine Damasceno, Ricardo Dias Portela, Ferlando Lima Santos, Genira Carneiro Araújo, Emanoel Ferreira Martins-Filho, Laís Pereira Silva, Thiago Doria Barral, Stefanie Alvarenga Santos, Alessandra Estrela-Lima

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Metabolic Alterations in Canine Mammary Tumors.Animals : an open access journal from MDPI · 2023
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Keidylania Costa-SantosEscola de Medicina Veterinária e Zootecnia, Universidade Federal da Bahia, Salvador, Bahia, 40170-110, Brazil.
Karine DamascenoInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Bahia, Brazil.
Ricardo Dias PortelaInstituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, Bahia, 40110-100, Brazil.
Ferlando Lima SantosUniversidade Federal do Recôncavo da Bahia, Santo Antônio de Jesus, Bahia, 44570-000, Brazil.
Genira Carneiro AraújoUniversidade do Estado da Bahia, Salvador, Bahia, 41195-001, Brazil.
Emanoel Ferreira Martins-FilhoEscola de Medicina Veterinária e Zootecnia, Universidade Federal da Bahia, Salvador, Bahia, 40170-110, Brazil.
Laís Pereira SilvaEscola de Medicina Veterinária e Zootecnia, Universidade Federal da Bahia, Salvador, Bahia, 40170-110, Brazil.
Thiago Doria BarralInstituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, Bahia, 40110-100, Brazil.
Stefanie Alvarenga SantosEscola de Medicina Veterinária e Zootecnia, Universidade Federal da Bahia, Salvador, Bahia, 40170-110, Brazil.
Alessandra Estrela-LimaEscola de Medicina Veterinária e Zootecnia, Universidade Federal da Bahia, Salvador, Bahia, 40170-110, Brazil. alestrela@gmail.com.
Universidade Federal da Bahia · BRFundação Oswaldo Cruz · BRInstituto Federal do Sertão Pernambucano · BRUniversidade do Estado da Bahia · BRUniversidade Federal do Recôncavo da Bahia · BR

Funding

Fundação de Amparo à Pesquisa do Estado da Bahia 023/2014
6 · The paper itself

Abstract

backgroundDyslipidemias induce angiogenesis and accelerate the development and in vitro growth of breast tumors. The aim of this study was to assess the lipid and metabolic profile of female dogs with mammary carcinomas and their correlations with body condition score and degree of tumor malignancy, as well as to study the effect of dietary fish oil supplementation on these animals.

resultsOverweight or obese dogs had more aggressive carcinomas and higher triglyceride (p = 0.0363), VLDL (p = 0.0181), albumin (p = 0.0188), globulin (p = 0.0145) and lactate (p = 0.0255) concentrations. There was no change in the lipid profile after supplementation with fish oil at any concentration. However, in relation to the metabolic profile, glucose (p = 0.0067), total protein (p = 0.0002) and globulin (p = 0.0002) concentrations were increased when 90% omega-3 fish oil was used as a dietary supplement.

conclusionObese dogs showed altered lipid and metabolic profiles and more aggressive tumors, suggesting an important relationship between dyslipidemia and tumor aggressiveness. Supplementation with fish oil, rich in omega-3 fatty acids, may alter metabolic parameters in cancer patients.

Indexed as

MetabolomeAnimalsCarcinomaDietary SupplementsDogsFemaleFish OilsLipidsMammary Neoplasms, AnimalMastectomyObesityOvariectomyFish OilsLipidsBreast cancerLipidsObesity

Identifiers

PMID31703601
PMCPMC6839264
OpenAlexW2989226118

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.