Evidence map›Paper›PMID 31712444›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

T6SS and ExoA of flesh-eating

Ana Fernández-Bravo, Paul B Kilgore, Jourdan A Andersson, Elizabeth Blears, Maria José Figueras, Nur A Hasan, Rita R Colwell, Jian Sha, Ashok K Chopra

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Pathogenic characterization ofFrontiers in cellular and infection microbiology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Interactions betweenFrontiers in microbiology · 2024
    Article
  9. Article
  10. Value of T6SS Core GeneIndian journal of microbiology · 2023
    Article
  11. Pathogens (Basel, Switzerland) · 2023
    Article
  12. Molecular Profiling of a Multi-Strain HypervirulentInfection and drug resistance · 2023
    Article
  13. Potential Pathogenicity ofPathogens (Basel, Switzerland) · 2022
    Article
  14. Article
  15. Article
  16. In silico comparative analysis of Aeromonas Type VI Secretion System.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  17. VasH Contributes to Virulence ofFrontiers in veterinary science · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Ana Fernández-BravoUnidad de Microbiología, Departamento de Ciencias Médicas Básicas, Facultad de Medicina y Ciencias de la Salud, Instituto de Investigación Sanitaria Pere Virgili, Universidad Rovira i Virgili, 43201 Reus, Spain.
Paul B KilgoreDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, 77555.
Jourdan A AnderssonDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, 77555.
Elizabeth BlearsDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, 77555.
Maria José FiguerasUnidad de Microbiología, Departamento de Ciencias Médicas Básicas, Facultad de Medicina y Ciencias de la Salud, Instituto de Investigación Sanitaria Pere Virgili, Universidad Rovira i Virgili, 43201 Reus, Spain.
Nur A HasanResearch and Development Department, CosmosID Inc., Rockville, MD 20850.
Rita R ColwellResearch and Development Department, CosmosID Inc., Rockville, MD 20850.
Jian ShaDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, 77555; jisha@utmb.edu achopra@utmb.edu.
Ashok K ChopraDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, 77555; jisha@utmb.edu achopra@utmb.edu.
The University of Texas Medical Branch at Galveston · USCosmos Corporation (United States) · USInstitut d'Investigació Sanitària Pere Virgili · ESBaylor College of Medicine · US

Funding

West African Center for Emerging Infectious DiseasesU01AI151801 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Robert W Cross, Scott C Weaver · 2020 to 2026
$10.1M
Biodefense Training ProgramT32AI060549 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI ASHOK K CHOPRA, Janice J Endsley · 2004 to 2026
$3.0M
Underlying mechanisms of necrotizing fasciitis during polymicrobial infectionsR21AI135453 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI CHOPRA, ASHOK K · 2018 to 2019
$434k
NIAID NIH HHS R21 AI135453NIAID NIH HHS T32 AI060549NIAID NIH HHS U01 AI151801
6 · The paper itself

Abstract

An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4

Indexed as

Bacterial ToxinsExotoxinsType VI Secretion SystemsAeromonas hydrophilaAnimalsCoinfectionFasciitis, NecrotizingHumansMetagenomeMicePeritonitisPhagocytosisVirulenceBacterial ToxinsExotoxinsType VI Secretion Systemsanimal modelsExoAmono- and polymicrobial Aeromonas hydrophila infectionsnecrotizing fasciitisT6SS

Identifiers

PMID31712444
PMCPMC6883842
OpenAlexW2986385050

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.