Evidence map›Paper›PMID 31717821›Full record

ArticleBiomolecules2019

Plant Polyphenols Inhibit Functional Amyloid and Biofilm Formation in

Zahra Najarzadeh, Hossein Mohammad-Beigi, Jannik Nedergaard Pedersen, Gunna Christiansen, Thorbjørn Vincent Sønderby, Seyed Abbas Shojaosadati, Dina Morshedi, Kristian Strømgaard, Georg Meisl, Duncan Sutherland and 2 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. The Importance of Being Imperfect: Structure and Function of Bacterial Amyloid.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  3. Review
  4. Frontiers in chemistry · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Anti-Biofilm Molecules Targeting Functional Amyloids.Antibiotics (Basel, Switzerland) · 2021
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Nanosilver Mitigates Biofilm Formation via FapC Amyloidosis Inhibition.Small (Weinheim an der Bergstrasse, Germany) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Zahra NajarzadehBiotechnology Group, Faculty of Chemical Engineering, Tarbiat Modares University, P.O. Box 14115-143, Tehran, Iran.
Hossein Mohammad-BeigiInterdisciplinary Nanoscience Centre (iNANO), Aarhus University, 8000 Aarhus C, Denmark.
Jannik Nedergaard PedersenInterdisciplinary Nanoscience Centre (iNANO), Aarhus University, 8000 Aarhus C, Denmark.
Gunna ChristiansenDepartment of Biomedicine-Medical Microbiology and Immunology, Aarhus University, 8000 Aarhus C, Denmark.
Thorbjørn Vincent SønderbyInterdisciplinary Nanoscience Centre (iNANO), Aarhus University, 8000 Aarhus C, Denmark.
Seyed Abbas ShojaosadatiBiotechnology Group, Faculty of Chemical Engineering, Tarbiat Modares University, P.O. Box 14115-143, Tehran, Iran.
Dina MorshediDepartment of Industrial and Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology, P.O. Box: 1417863171, Tehran, Iran.
Kristian StrømgaardDepartment of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen Ø, Denmark.ORCID 0000-0003-2206-4737
Georg MeislDepartment of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.ORCID 0000-0002-6562-7715
Duncan SutherlandInterdisciplinary Nanoscience Centre (iNANO), Aarhus University, 8000 Aarhus C, Denmark.
Jan Skov PedersenInterdisciplinary Nanoscience Centre (iNANO), Aarhus University, 8000 Aarhus C, Denmark.
Daniel E OtzenInterdisciplinary Nanoscience Centre (iNANO), Aarhus University, 8000 Aarhus C, Denmark.ORCID 0000-0002-2918-8989
Aarhus University · DKTarbiat Modares University · IRUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Self-assembly of proteins to β-sheet rich amyloid fibrils is commonly observed in various neurodegenerative diseases. However, amyloid also occurs in the extracellular matrix of bacterial biofilm, which protects bacteria from environmental stress and antibiotics. Many

Indexed as

AmyloidBiofilmsCatechinFungal ProteinsHydrolyzable TanninsPolyphenolsProtein AggregatesPseudomonasAmyloidCatechinepigallocatechin gallateFungal ProteinsHydrolyzable TanninspentagalloylglucosePolyphenolsProtein Aggregatesaggregation inhibitorbacterial amyloidextracellular matrixFapC proteinpeptide array

Identifiers

PMID31717821
PMCPMC6920965
OpenAlexW2981733277

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.