Evidence map›Paper›PMID 31724335›Full record

ArticlePhysiological reports2019

Hypovolemia and reduced hemoglobin mass in patients with heart failure and preserved ejection fraction.

David Montero, Thomas Haider, Jens Barthelmes, Jens P Goetze, Silviya Cantatore, Isabella Sudano, Frank Ruschitzka, Andreas J Flammer

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Why are SGLT2 inhibitors effective in HFpEF? Implications for interstitial fluid retention and cardio-renal interaction.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Review
  3. Article
  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

David MonteroUniversity Heart Center, University Hospital Zurich, Zurich, Switzerland.ORCID 0000-0002-0438-8271
Thomas HaiderInstitute of Physiology, University of Zurich, Zurich, Switzerland.
Jens BarthelmesUniversity Heart Center, University Hospital Zurich, Zurich, Switzerland.
Jens P GoetzeDepartment of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Silviya CantatoreUniversity Heart Center, University Hospital Zurich, Zurich, Switzerland.
Isabella SudanoUniversity Heart Center, University Hospital Zurich, Zurich, Switzerland.
Frank RuschitzkaUniversity Heart Center, University Hospital Zurich, Zurich, Switzerland.
Andreas J FlammerUniversity Heart Center, University Hospital Zurich, Zurich, Switzerland.
University Hospital of Zurich · CHUniversity of Copenhagen · DKUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A fundamental tenet of heart failure (HF) pathophysiology hinges on a propensity for fluid retention leading to blood volume (BV) expansion and hemodilution. Whether this can be applied to heart failure patients with preserved ejection fraction (HFpEF) remains uncertain. The present study sought to determine BV status and key hormones regulating fluid homeostasis and erythropoiesis in HFpEF patients. BV and hemoglobin mass (Hb

Indexed as

AgedErythropoiesisFemaleHeart FailureHomeostasisHumansHypovolemiaMaleStroke VolumeVascular StiffnessBlood volumeerythropoietinheart failure with preserved ejection fractionhemoglobin mass

Identifiers

PMID31724335
PMCPMC6854115
OpenAlexW2988750108

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.