Evidence map›Paper›PMID 31726205›Full record

ArticleBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2020

Predictors of Loss to Follow-Up Among Pediatric and Adult Hematopoietic Cell Transplantation Survivors: A Report from the Center for International Blood and Marrow Transplant Research.

David Buchbinder, Ruta Brazauskas, Khalid Bo-Subait, Karen Ballen, Susan Parsons, Tami John, Theresa Hahn, Akshay Sharma, Amir Steinberg, Anita D'Souza and 46 more

Open access · bronzeAbstract read
In one paragraph

Article in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

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  15. Driving Distance and Patient-Reported Outcomes in Hematopoietic Cell Transplantation Survivors.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

56 authors at 20 institutions in 10 countries.

David BuchbinderDivision of Pediatric Hematology, Children's Hospital of Orange County, Orange, California. Electronic address: dbuchbinder@choc.org.
Ruta BrazauskasCenter for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Khalid Bo-SubaitCenter for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Karen BallenDivision of Hematology/Oncology, University of Virginia Health System, Charlottesville, Virginia.
Susan ParsonsThe Center for Health Solutions at the Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts.
Tami JohnDepartment of Pediatrics, Section of Hematology/Oncology, Baylor College of Medicine Center for Cell and Gene Therapy, Houston, Texas.
Theresa HahnDepartment of Medicine, Roswell Park Cancer Institute, Buffalo, New York.
Akshay SharmaDepartment of Bone Marrow Transplantation and Cellular Therapy, St Jude Children's Research Hospital, Memphis, Tennessee.
Amir SteinbergDivision of Hematology and Oncology, Mount Sinai Hospital, New York, New York.
Anita D'SouzaCenter for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Anita J KumarThe Center for Health Solutions at the Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts.
Ayami YoshimiDepartment of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University of Freiburg Medical Center, Freiburg, Germany.
Baldeep WirkDivision of Bone Marrow Transplant, Seattle Cancer Care Alliance, Seattle, Washington.
Bronwen ShawCenter for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
César FreytesTexas Transplant Institute, San Antonio, Texas.
Charles LeMaistreHematology and Bone Marrow Transplant, Sarah Cannon, Nashville, Tennessee.
Christopher BredesonOttawa Hospital Blood and Marrow Transplant Program and Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Christopher DandoyUC Department of Pediatrics and Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
David AlmaguerHematology Service at the University Hospital in Monterrey Mexico, and the Stem cell Transplantation Program, Hospital Universitario Dr José E. González, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Mexico.
David I MarksAdult Bone Marrow Transplant, University Hospitals Bristol NHS Trust, Bristol, United Kingdom.
David SzwajcerDepartment of Hematology/Oncology, CancerCare Manitoba/University of Manitoba, Winnipeg, Manitoba, Canada.
Gregory HaleDepartment of Hematology/Oncology, Johns Hopkins All Children's Hospital, St Petersburg, Florida.
Harry SchoutenDepartment of Hematology, Academische Ziekenhuis, Maastricht, The Netherlands.
Hasan HashemDivision of Pediatric Hematology/Oncology and Bone marrow Transplantation, King Hussein Cancer Center, Amman, Jordan.
Hélène SchoemansHematology department and Bone marrow transplant unit, University Hospital Leuven and KU Leuven, Leuven, Belgium.
Hemant S MurthyMayo Clinic Florida, Jacksonville, Florida.
Hillard M LazarusDepartment of Medicine, Case Western Reserve University, Cleveland, Ohio.
Jan CernyDivision of Hematology/Oncology, Department of Medicine, University of Massachusetts Medical Center, Worcester, Massachusetts.
Jason TayTom Baker Cancer Centre, University of Calgary, Calgary, Alberta, Canada.
Jean A YaredBlood & Marrow Transplantation Program, Division of Hematology/Oncology, Department of Medicine, Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Maryland.
Kehinde AdekolaDivision of Hematology/Oncology, Department of Medicine and Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Kirk R SchultzDepartment of Pediatric Hematology, Oncology and Bone Marrow Transplant, British Columbia's Children's Hospital, The University of British Columbia, Vancouver, British Columbia, Canada.
Leslie LehmannDana-Farber Cancer Institute/Boston Children's Hospital, Boston, Massachusetts.
Linda BurnsCenter for International Blood and Marrow Transplant Research, National Marrow Donor Program/Be The Match, Minneapolis, Minnesota.
Mahmoud AljurfDepartment of Oncology, King Faisal Specialist Hospital Center & Research, Riyadh, Saudi Arabia.
Miguel Angel DiazDepartment of Hematology/Oncology, Hospital Infantil Universitario Nino Jesus, Madrid, Spain.
Navneet MajhailBlood & Marrow Transplant Program, Cleveland Clinic Taussig Cancer Institute, Cleveland, Ohio.
Nosha FarhadfarDivision of Hematology/Oncology, University Florida College of Medicine, Gainesville, Florida.
Rammurti KambleDivision of Hematology and Oncology, Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas.
Richard OlssonDepartment of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Centre for Clinical Research Sormland, Uppsala University, Uppsala, Sweden.
Raquel SchearsDepartment of Emergency Medicine, University of Central Florida, Orlando, Florida.
Sachiko SeoDepartment of Hematology and Oncology, Dokkyo Medical University, Tochigi, Japan.
Sara BeattieDepartment of Psychosocial Oncology and Rehabilitation, Tom Baker Cancer Centre, Calgary, Alberta, Canada; Tom Baker Cancer Centre, University of Calgary, Calgary, Alberta, Canada.
Saurabh ChhabraCenter for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Bipin N SavaniDivision of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Sherif BadawyDivision of Hematology, Oncology and Stem Cell Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Siddhartha GangulyDivision of Hematological Malignancy and Cellular Therapeutics, University of Kansas Health System, Kansas City, Kansas.
Stefan CiureaMD Anderson Cancer Center, Houston, Texas.
Susana MarinoDepartment of Pathology, University of Chicago Medicine, Chicago, Illinois.
Usama GergisHematologic Malignancies & Bone Marrow Transplant, Department of Medical Oncology, New York Presbyterian Hospital/Weill Cornell Medical Center, New York, New York.
Yachiyo KuwatsukaDepartment of Advanced Medicine, Nagoya University Hospital, Nagoya, Japan.
Yoshihiro InamotoDivision of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
Nandita KheraDepartment of Hematology/Oncology, Mayo Clinic, Phoenix, Arizona.
Shahrukh HashmiDepartment of Oncology, King Faisal Specialist Hospital Center & Research, Riyadh, Saudi Arabia; Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.
William WoodDivision of Hematology/Oncology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina.
Wael SaberCenter for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Medical College of Wisconsin · USBaylor College of Medicine · USNorthwestern University · USTufts Medical Center · USUniversity of Calgary · CABoston Children's Hospital · USCancerCare Manitoba · CACase Western Reserve University · USChildren's Hospital of Orange County · USCHRISTUS Transplant Institute · USCincinnati Children's Hospital Medical Center · USCleveland Clinic · USDokkyo Medical University · JPFlorida College · USHospital Infantil Universitario Niño Jesús · ESJacksonville College · USJohns Hopkins University · USKing Faisal Specialist Hospital & Research Centre · SAKing Hussein Cancer Center · JOKU Leuven · BE

Funding

Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
An mHealth Strategy to Improve Medication Adherence in Adolescents with Sickle Cell DiseaseK23HL150232 · NHLBI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI BADAWY, SHERIF MOHAMED · 2020 to 2024
$842k
NCI NIH HHS U24 CA076518NHLBI NIH HHS K23 HL150232
6 · The paper itself

Abstract

Follow-up is integral for hematopoietic cell transplantation (HCT) care to ensure surveillance and intervention for complications. We characterized the incidence of and predictors for being lost to follow-up. Two-year survivors of first allogeneic HCT (10,367 adults and 3865 children) or autologous HCT (7291 adults and 467 children) for malignant/nonmalignant disorders between 2002 and 2013 reported to the Center for International Blood and Marrow Transplant Research were selected. The cumulative incidence of being lost to follow-up (defined as having missed 2 consecutive follow-up reporting periods) was calculated. Marginal Cox models (adjusted for center effect) were fit to evaluate predictors. The 10-year cumulative incidence of being lost to follow-up was 13% (95% confidence interval [CI], 12% to 14%) in adult allogeneic HCT survivors, 15% (95% CI, 14% to 16%) in adult autologous HCT survivors, 25% (95% CI, 24% to 27%) in pediatric allogeneic HCT survivors, and 24% (95% CI, 20% to 29%) in pediatric autologous HCT survivors. Factors associated with being lost to follow-up include younger age, nonmalignant disease, public/no insurance (reference: private), residence farther from the tranplantation center, and being unmarried in adult allogeneic HCT survivors; older age and testicular/germ cell tumor (reference: non-Hodgkin lymphoma) in adult autologous HCT survivors; older age, public/no insurance (reference: private), and nonmalignant disease in pediatric allogeneic HCT survivors; and older age in pediatric autologous HCT survivors. Follow-up focusing on minimizing attrition in high-risk groups is needed to ensure surveillance for late effects.

Indexed as

Hematopoietic Stem Cell TransplantationAdultAgedChildFollow-Up StudiesHumansSurvivorsTransplantation ConditioningTransplantation, HomologousBone marrow transplantationLost to follow-upStem cell transplantationSurvivor

Identifiers

PMID31726205
PMCPMC7367505
OpenAlexW2989343462

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.