ReviewFrontiers in bioengineering and biotechnology2019
Raman Spectroscopy: Guiding Light for the Extracellular Matrix.
Review in Frontiers in bioengineering and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
69 citing papers in PubMed.
- Label-Free Hyperspectral Raman Imaging and Analysis of a 3D Spheroid Model for Liver Fibrosis Study.Chemical & biomedical imaging · 2026Article
- Magnetic resonance and X-ray contrast agents in the optical clearing of dermis - insights fromBiomedical optics express · 2026Article
- hBM-MSC-Laden 3D Bioprinted Gelatin-Alginate Hydrogels: Physicochemical Characterisation and Osteogenic Lineage Commitment.Gels (Basel, Switzerland) · 2026Article
- Label-free in vivo molecular profiling of the human retina by non-resonant Raman spectroscopy.Communications biology · 2026Article
- Raman Investigation of Cardiac Tissues with Sodium-Induced High Stiffness.Molecules (Basel, Switzerland) · 2026Article
- The mechanical strain as a cross-linking agent for skeletal muscle ECM-derived hydrogels.Materials today. Bio · 2026Article
- Rethinking osteocyte modelsFrontiers in bioengineering and biotechnology · 2026Review
- Confocal Raman microspectroscopy imaging reveals structural protein reorganization in human intracranial aneurysm tissue.Scientific reports · 2025Article
- Review
- Integrated nanoindentation-Raman spectroscopy reveals microscale biomechanical and molecular biomarkers of early intervertebral disc degeneration in a rat model.Materials today. Bio · 2025Article
- Synergistic Effects of Non-Ionizing Radiation in the Targeted Modification of Living Tissues.International journal of molecular sciences · 2025Review
- Engineering Nanomaterials for Raman Bioimaging and Theranostics: Advances, Challenges, and Future Directions.ACS omega · 2025Review
- Bioinspired Collagen/κ-Carrageenan 3D Matrix forACS biomaterials science & engineering · 2025Article
- Polymicrobial Biofilms: Interkingdom Interactions, Resistance and Therapeutic Strategies.Microbial biotechnology · 2025Review
- Characterizing Variability in Non-Invasive Hydration Monitoring Using Raman Spectroscopy.Applied spectroscopy · 2025Article
- Multiparametric physicochemical analysis of a type 1 collagen 3D cell culture model using light and electron microscopy and mass spectrometry imaging.Scientific reports · 2025Article
- Solid-State NMR Spectroscopy Investigation of Structural Changes of Mechanically Strained Mouse Tail Tendons.Journal of the American Chemical Society · 2025Article
- High-Throughput Single-Cell Analysis of Local Nascent Protein Deposition in 3D Microenvironments via Extracellular Protein Identification Cytometry (EPIC).Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Development of a label-free, functional, molecular and structural imaging system combining optical coherence tomography and Raman spectroscopy for in vivo measurement of rat retina.Biomedical optics express · 2025Article
- To Acquire or Not to Acquire: Evaluating Compressive Sensing for Raman Spectroscopy in Biology.ACS sensors · 2025Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The extracellular matrix (ECM) consists of a complex mesh of proteins, glycoproteins, and glycosaminoglycans, and is essential for maintaining the integrity and function of biological tissues. Imaging and biomolecular characterization of the ECM is critical for understanding disease onset and for the development of novel, disease-modifying therapeutics. Recently, there has been a growing interest in the use of Raman spectroscopy to characterize the ECM. Raman spectroscopy is a label-free vibrational technique that offers unique insights into the structure and composition of tissues and cells at the molecular level. This technique can be applied across a broad range of ECM imaging applications, which encompass
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.