Evidence map›Paper›PMID 31737655›Full record

ReviewBioMed research international2019

The Prominent Role of HMGA Proteins in the Early Management of Gastrointestinal Cancers.

Nathalia Meireles Da Costa, Luis Felipe Ribeiro Pinto, Luiz Eurico Nasciutti, Antonio Palumbo

Abstract readReview
In one paragraph

Review in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nathalia Meireles Da CostaPrograma de Carcinogênese Molecular, Instituto Nacional de Câncer José de Alencar Gomes da Silva, Rio de Janeiro, RJ, Brazil.
Luis Felipe Ribeiro PintoPrograma de Carcinogênese Molecular, Instituto Nacional de Câncer José de Alencar Gomes da Silva, Rio de Janeiro, RJ, Brazil.
Luiz Eurico NasciuttiLaboratório de Interações Celulares, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.ORCID https://orcid.org/0000-0002-2597-793X
Antonio PalumboLaboratório de Interações Celulares, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.ORCID https://orcid.org/0000-0002-7977-8522

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GI tumors represent a heterogeneous group of neoplasms concerning their natural history and molecular alterations harbored. Nevertheless, these tumors share very high incidence and mortality rates worldwide and patients' poor prognosis. Therefore, the identification of specific biomarkers could increase the development of personalized medicine, in order to improve GI cancer management. In this sense, HMGA family members (HMGA1 and HMGA2) comprise an important group of genes involved in the genesis and progression of malignant tumors. Additionally, it has also been reported that HMGA1 and HMGA2 display an important role in the detection and progression of GI tumors. In this way, HMGA family members could be used as reliable biomarkers able to efficiently track not only the tumor

Indexed as

AnimalsBiomarkers, TumorDisease ProgressionGastrointestinal NeoplasmsHMGA ProteinsHumansPrognosisBiomarkers, TumorHMGA Proteins

Identifiers

PMID31737655
PMCPMC6815579

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.