Evidence map›Paper›PMID 31739532›Full record

ArticleNutrients2019

Tamarind Trypsin Inhibitor in Chitosan-Whey Protein Nanoparticles Reduces Fasting Blood Glucose Levels without Compromising Insulinemia: A Preclinical Study.

Lídia L R Matias, Rafael O A Costa, Thaís S Passos, Jaluza L C Queiroz, Alexandre C Serquiz, Bruna L L Maciel, Pedro P A Santos, Christina S Camillo, Catarina Gonçalves, Isabel R Amado and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. ProspectingJournal of enzyme inhibition and medicinal chemistry · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Encapsulated Peptides and Proteins with an Effect on Satiety.Nanomaterials (Basel, Switzerland) · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Synthesis ofVaccines · 2021
    Article
  17. Safety and bioactive potential of nanoparticles containing Cantaloupe melon (Biotechnology reports (Amsterdam, Netherlands) · 2020
    Article
  18. Drug target insights
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 3 countries.

Lídia L R MatiasNutrition Postgraduate Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970, Brazil.
Rafael O A CostaBiochemistry Postgraduate Program, Biosciences Center, Federal University of Rio Grande do Norte, Natal, RN 59078-970, Brazil.
Thaís S PassosDepartment of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970, Brazil.
Jaluza L C QueirozBiochemistry Postgraduate Program, Biosciences Center, Federal University of Rio Grande do Norte, Natal, RN 59078-970, Brazil.
Alexandre C SerquizCourse of Nutrition, Center University of Rio Grande do Norte, Natal, RN 59014-545, Brazil.
Bruna L L MacielNutrition Postgraduate Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970, Brazil.ORCID 0000-0002-0724-1961
Pedro P A SantosStructural and Functional Biology Postgraduate Program, Biosciences Center, Federal University of Rio Grande do Norte, Natal, RN 59078-970, Brazil.
Christina S CamilloStructural and Functional Biology Postgraduate Program, Biosciences Center, Federal University of Rio Grande do Norte, Natal, RN 59078-970, Brazil.
Catarina GonçalvesInternational Iberian Nanotechnology Laboratory, 4715-330 Braga, Portugal.ORCID 0000-0002-7121-6875
Isabel R AmadoInternational Iberian Nanotechnology Laboratory, 4715-330 Braga, Portugal.
Lorenzo PastranaInternational Iberian Nanotechnology Laboratory, 4715-330 Braga, Portugal.
Ana H A MoraisNutrition Postgraduate Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970, Brazil.ORCID 0000-0002-6460-911X
Universidade Federal do Rio Grande do Norte · BRInternational Iberian Nanotechnology Laboratory · PT

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 426116/2018-6H2020 Marie Skłodowska-Curie Research and Innovation Staff Exchange 031716
6 · The paper itself

Abstract

In vivo studies show the benefits of the trypsin inhibitor isolated from tamarind (

Indexed as

NanoparticlesAnimalsBlood GlucoseChitosanCholesterol, HDLDelayed-Action PreparationsDietFastingGlycemic IndexHydrolysisHyperglycemiaHypoglycemic AgentsInsulinInsulin ResistanceMalePancreasBlood GlucoseChitosanCholesterol, HDLDelayed-Action PreparationsHypoglycemic AgentsInsulinPlant ExtractsTrypsinTrypsin InhibitorsWhey Proteinsdigestionencapsulationfasting glucoseinsulinoverfeedingTamarindusindica L.

Identifiers

PMID31739532
PMCPMC6893787
OpenAlexW2986156039

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.