SynthesisOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2020
Association between postoperative delirium and mortality in elderly patients undergoing hip fractures surgery: a meta-analysis.
Synthesis in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 104 citations in OpenAlex.
- Association between hyperlipidemia and postoperative delirium risk: a systematic review and meta-analysis.Frontiers in aging neuroscience · 2025Pooled it
- Association between frailty and postoperative delirium: a meta-analysis of cohort study.Aging clinical and experimental research · 2022Pooled it
- Occupational Therapy for Establishing a Morning Routine to Prevent Delirium After Hip Fracture Surgery: A Randomised Controlled Feasibility Study.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2025Trial
- Overtime work of anesthesiologists is associated with increased delirium in older patients admitted to intensive care unit after noncardiac surgery: a secondary analysis.BMC anesthesiology · 2024Trial
- Early Intervention of Perioperative Delirium in Older Patients (>60 years) with Hip Fracture: A Randomized Controlled Study.Orthopaedic surgery · 2022Trial
- Pre-Fracture Cognitive Assessment Using the DASC-21 and Postoperative Delirium Risk.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2026Article
- Association of pre- and postoperative delirium with functional status at discharge after hip fracture: findings from the Gruppo Italiano di Ortogeriatria (GIOG 2.0) study.European geriatric medicine · 2026Article
- Associations between polygenic risk scores for Alzheimer's disease and postoperative delirium risk.Journal of Alzheimer's disease : JAD · 2026Article
- Validity and Reliability of the Thai Version of the Delirium Diagnostic Tool-Provisional (DDT-Pro-TH) in Perioperative Patients With Fragility Hip Fractures.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Plasma-Derived Exosomal hsa-miR-3677-3p Induces Ferroptosis in Neurons by Targeting ABCB8 in Perioperative Neurocognitive Disorders After Prostate Surgery.Neurochemical research · 2026Article
- Integrating Clinical Information and Electrocardiographic Signal Features to Develop a Prediction Model for Postoperative Delirium in Older Patients: A Prospective Observational Study.International journal of general medicine · 2026Article
- The association between peripheral nerve blocks and postoperative delirium in adults undergoing hip fracture surgery: a systematic review and meta-analysis.Arthroplasty (London, England) · 2025Review
- The effect of enhanced recovery after surgery on postoperative delirium in surgical patients: a meta-analysis.Annals of surgical treatment and research · 2025Article
- Article
- Enhancing Cognitive Impairment Assessment and Management in Hip Fracture Patients: A Two-Cycle Clinical Audit.Cureus · 2025Article
- Creating a delirium risk assessment model for geriatric patients with femoral neck fractures through artificial intelligence techniques: a theoretical exploration.BMC neurology · 2025Article
- Article
- Trends and Mortality Predictors of Delirium Among Hospitalized Older Adults: A National 5-Year Retrospective Study in Thailand.Geriatrics (Basel, Switzerland) · 2025Article
- Incidence and Risk Factors of Postoperative Delirium in Elderly Patients Following Hip Fracture Surgery: A Nationwide Retrospective Cohort Study in Taiwan.International journal of geriatric psychiatry · 2025Article
- Validation of the Frail-VIG frailty index in geriatric population with femur fracture.European geriatric medicine · 2025Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
introductionPostoperative delirium (POD) is a common complication in elderly surgical patients. Patients undergoing hip fractures surgery who are often characterized by advanced age could be particularly prone to suffering POD. We performed a meta-analysis to assess the association between POD and mortality in elderly patients undergoing hip fractures surgery. This meta-analysis included twenty-one cohort studies, and the pooled outcomes demonstrated that approximated one-fourth of patients undergoing hipfracture surgery would develop POD, and delirium increased the mortality in these patients.
methodsWe searched PubMed, Embase, Web of Science, and Scopus for studies that investigated the effect of POD on mortality in elderly patients undergoing hip fracture surgery. Two reviewers independently selected studies, assessed quality, and extracted data. Statistical analyses were performed by STATA 14.0 and RevMan 5.3. Risk ratios (RRs) with 95% confidence intervals (CIs) were derived using random or fixed-effects model.
resultsTwenty-one cohort studies enrolling a total of 6288 patients were included, and the pooled prevalence (95% CI) of POD was 28% (23-34%). POD was associated with an increase in perioperative mortality (30-day or in-hospital mortality) [12 studies, 3123 patients, relative risk (RR) (95% CI) 2.79 (1.97-3.93)], 6-month mortality [6 studies, 1673 patients, 2.51 (1.99-3.16)], 1-year mortality [6 studies, 1896 patients, 1.98 (1.62-2.41)], and more than 1-year mortality [8 studies, 1926 patients, 2.06 (1.60-2.64)].
conclusionsOur meta-analysis demonstrated that approximated one-fourth of patients undergoing hip fracture surgery would develop POD, and delirium increased the short-term and long-term mortality in these patients.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.