Evidence map›Paper›PMID 31744366›Full record

ArticleAutophagy2020

Restriction of intracellular

Veena Ammanathan, Piyush Mishra, Aravinda K Chavalmane, Sasikumar Muthusamy, Vidya Jadhav, Chandrashekaran Siddamadappa, Ravi Manjithaya

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Review
  4. Restricting intracellularAutophagy · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Journal of bacteriology · 2024
    Article
  10. Evolution of innate immunity: lessons from mammalian models shaping our current view of insect immunity.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024
    Review
  11. Microbiology spectrum · 2024
    Article
  12. Complement C3 deposition restricts the proliferation of internalizedFrontiers in cellular and infection microbiology · 2024
    Article
  13. Article
  14. Autophagy-dependent ferroptosis in infectious disease.Journal of translational internal medicine · 2023
    Article
  15. Review
  16. Review
  17. Article
  18. p38Frontiers in immunology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 4 countries.

Veena AmmanathanAutophagy Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research , Bangalore, India.
Piyush MishraAutophagy Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research , Bangalore, India.
Aravinda K ChavalmaneAutophagy Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research , Bangalore, India.
Sasikumar MuthusamyVipragen Biosciences Private Limited , Mysuru, India.
Vidya JadhavAutophagy Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research , Bangalore, India.
Chandrashekaran SiddamadappaVipragen Biosciences Private Limited , Mysuru, India.
Ravi ManjithayaAutophagy Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research , Bangalore, India.
Jawaharlal Nehru Centre for Advanced Scientific Research · INThomas Jefferson University · US

Funding

Wellcome Trust
6 · The paper itself

Abstract

Macroautophagy/autophagy functions as a part of the innate immune system in clearing intracellular pathogens. Although this process is well known, the mechanisms that control antibacterial autophagy are not clear. In this study we show that during intracellular ABBREVIATIONS: 3-MA: 3-methyladenine; BafA1: bafilomycin A

Indexed as

AutophagyAnimalsBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsDisease Models, AnimalFlavonesHeLa CellsHumansIntracellular SpaceLysosomesMicePhosphorylationProteolysisRAW 264.7 CellsSaccharomyces cerevisiaeSalmonella typhimuriumVacuolesacacetinBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsFlavonesTFEB protein, humanAcacetinautolysosomeslysosomesMTOR-independentSalmonella-containing vacuolesSalmonella typhimuriumTFEBxenophagy

Identifiers

PMID31744366
PMCPMC8386624
OpenAlexW2989984439

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.