ReviewAntioxidants (Basel, Switzerland)2019
Redox Regulation and Oxidative Stress: The Particular Case of the Stallion Spermatozoa.
Review in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 94 citations in OpenAlex.
- Effect of Uncoated Magnetic Nanoparticles on Stallion Sperm Parameters: Influence of Semen Quality.Reproduction in domestic animals = Zuchthygiene · 2026Article
- The effect of fenugreek (Trigonella foenum-graecum) on stallion spermatozoa motility and vitality in vitro.Veterinary research communications · 2026Article
- Effect of Spirulina platensis extract (C-phycocyanin) supplementation to the semen extender on kinematic and oxidative parameters of Marwari stallions during freezing.Tropical animal health and production · 2026Article
- Holotomography and Multivariate Analysis Reveal Donor-Specific Responses to Antioxidant Supplementation During Stallion Sperm Cryopreservation.Antioxidants (Basel, Switzerland) · 2026Article
- Article
- Probiotic Supplementation as an Alternative to Antibiotics in Bovine Sperm Cryopreservation: Effects on Motility, Oxidative Stress and Apoptosis.Reproduction in domestic animals = Zuchthygiene · 2026Article
- Sixty-day oral antioxidant supplementation enhances sperm morphology and seminal plasma antioxidant capacity in stallions.Journal of animal science · 2026Article
- Association of semen leukocytes with sperm DNA fragmentation in a clinical cohort.Frontiers in endocrinology · 2026Article
- Relationships Between Metabolism of Cryopreserved Equine Sperm Determined by the Seahorse Analyzer and Sperm Characteristics Measured by Flow Cytometry and Computer-Assisted Analysis of Motility.Veterinary sciences · 2025Article
- Guilu Erxian oral liquid mitigates oxidative damage in spermatogonial cellsEuropean journal of histochemistry : EJH · 2025Article
- Dose-Dependent Effects of L-Serine Supplementation on Boar Sperm Quality During Chilled and Cryopreserved Storage.Animals : an open access journal from MDPI · 2025Article
- Challenges and Enhancing Strategies of Equine Semen Preservation: Nutritional and Genetic Perspectives.Veterinary sciences · 2025Review
- Effect of Centrifugation of Stallion Semen Through a Low Density Colloid Prior to Freezing on Sperm Cryosurvival.Animals : an open access journal from MDPI · 2025Article
- Cryopreservation Strategies for Poultry Semen: A Comprehensive Review of Techniques and Applications.Veterinary sciences · 2025Review
- Evaluating the Protective Effects of MitoQ and Antifreeze Protein III on Cryopreserved Canine Sperm.Animals : an open access journal from MDPI · 2025Article
- The Role of Melatonin on Caprine (Antioxidants (Basel, Switzerland) · 2024Review
- The effect of bee drone brood on the motility and viability of stallion spermatozoa-an in vitro study.In vitro cellular & developmental biology. Animal · 2024Article
- Advancements in Understanding and Enhancing Antioxidant-Mediated Sperm Cryopreservation in Small Ruminants: Challenges and Perspectives.Antioxidants (Basel, Switzerland) · 2024Review
- Impact of Seminal Plasma Antioxidants on DNA Fragmentation and Lipid Peroxidation of Frozen-Thawed Horse Sperm.Antioxidants (Basel, Switzerland) · 2024Article
- The Direct Effects of Climate Change on Tench (Animals : an open access journal from MDPI · 2024Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Redox regulation and oxidative stress have become areas of major interest in spermatology. Alteration of redox homeostasis is recognized as a significant cause of male factor infertility and is behind the damage that spermatozoa experience after freezing and thawing or conservation in a liquid state. While for a long time, oxidative stress was just considered an overproduction of reactive oxygen species, nowadays it is considered as a consequence of redox deregulation. Many essential aspects of spermatozoa functionality are redox regulated, with reversible oxidation of thiols in cysteine residues of key proteins acting as an "on-off" switch controlling sperm function. However, if deregulation occurs, these residues may experience irreversible oxidation and oxidative stress, leading to malfunction and ultimately death of the spermatozoa. Stallion spermatozoa are "professional producers" of reactive oxygen species due to their intense mitochondrial activity, and thus sophisticated systems to control redox homeostasis are also characteristic of the spermatozoa in the horse. As a result, and combined with the fact that embryos can easily be collected in this species, horses are a good model for the study of redox biology in the spermatozoa and its impact on the embryo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.