Evidence map›Paper›PMID 31753783›Full record

ArticleNutrition, metabolism, and cardiovascular diseases : NMCD2020

Alcohol consumption and subclinical atherosclerosis among South Asians: Findings from the Mediators of Atherosclerosis in South Asians Living in America (MASALA) study.

Parag A Chevli, Amer I Aladin, Alka M Kanaya, Namratha R Kandula, Diego Malaver, David M Herrington

Open access · bronzeAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Nutrition, metabolism, and cardiovascular diseases : NMCD, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Alcohol Consumption Patterns: A Systematic Review of Demographic and Sociocultural Influencing Factors.International journal of environmental research and public health · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Subclinical cardiovascular disease and utility of coronary artery calcium score.International journal of cardiology. Heart & vasculature · 2021
    Review
  6. Alcohol and Metabolic-associated Fatty Liver Disease.Journal of clinical and translational hepatology · 2021
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Parag A ChevliDepartment of Internal Medicine, Section on Hospital Medicine, Wake Forest School of Medicine, United States. Electronic address: pchevli@wakehealth.edu.
Amer I AladinDepartment of Internal Medicine, Section on Cardiovascular Medicine, Wake Forest School of Medicine, United States.
Alka M KanayaDepartment of Medicine, University of California San Francisco, United States.
Namratha R KandulaDepartment of Medicine, Northwestern University Feinberg School of Medicine, United States.
Diego MalaverDepartment of Internal Medicine, Section on Cardiovascular Medicine, Wake Forest School of Medicine, United States.
David M HerringtonDepartment of Internal Medicine, Section on Cardiovascular Medicine, Wake Forest School of Medicine, United States.
Wake Forest University · USNorthwestern University · USUniversity of California, San Francisco · US

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
Mediators of Atherosclerosis in South Asians Living in AmericaR01HL093009 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M. · 2010 to 2018
$5.4M
Ectopic fat and atherosclerosis in South AsiansK24HL112827 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M. · 2013 to 2022
$1.2M
NCRR NIH HHS UL1 RR024131NHLBI NIH HHS K24 HL112827NHLBI NIH HHS R01 HL093009NIDDK NIH HHS P30 DK092924NIDDK NIH HHS P30 DK098722
6 · The paper itself

Abstract

backgroundSouth Asians are the second fastest growing ethnic group in the United States, and they have a high risk for cardiovascular disease (CVD). Moderate alcohol consumption has been associated with lower CVD risk in some race/ethnic groups, but the association of alcohol consumption and atherosclerosis in South Asians has not been investigated. METHODS AND

resultsWe used data from 906 South Asian participants who participated in the Mediators of Atherosclerosis in South Asians Living in America (MASALA) cohort (2010-2012). Alcohol consumption was ascertained via questionnaire, coronary artery calcium (CAC) was measured with computed tomography, and common carotid artery intima-media thickness (cIMT) was measured using B-mode ultrasonography. We used multivariable regression models to examine cross-sectional associations of alcohol consumption with the presence and amount of CAC and cIMT. Compared with never drinkers, participants consuming 4-7 drinks/week had a 63% decreased odds of any CAC after adjusting for potential confounders and mediators. Participants consuming 4-7 drinks/week had significantly lower odds of CAC score between 1 and 300 [OR (95% CI): 0.34 (0.16-0.72)]. A similar inverse association was seen for the odds of CAC>300 [OR (95% CI): 0.28 (0.07-0.97)]. Alcohol consumption of >7 drinks/week was associated with a 0.096 mm increase in common-cIMT.

conclusionThere was an inverse association between the amount of alcohol intake and CAC among South Asians while a positive association was found between alcohol consumption and common-cIMT. Long-term follow-up of the MASALA cohort will examine prospective associations of alcohol intake with the progression of subclinical atherosclerosis, incident CVD events, and mortality.

Indexed as

AsianAdultAgedAged, 80 and overAlcohol DrinkingAsymptomatic DiseasesCarotid Artery DiseasesChicagoCoronary Artery DiseaseFemaleHumansIncidenceMaleMiddle AgedPrevalenceProspective StudiesAlcoholCoronary artery calciumSouth AsianSubclinical atherosclerosis

Identifiers

PMID31753783
PMCPMC6934907
OpenAlexW2965231711

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.