Evidence map›Paper›PMID 31759576›Full record

ReviewNeuroimaging clinics of North America2020

The Neurodevelopment of Autism from Infancy Through Toddlerhood.

Jessica B Girault, Joseph Piven

Open access · greenAbstract readReview
In one paragraph

Review in Neuroimaging clinics of North America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Atypical structural connectivity of language networks in autism spectrum disorder: A meta-analysis of diffusion tensor imaging studies.Autism research : official journal of the International Society for Autism Research · 2022
    Pooled it
  3. Article
  4. Early autism risk factors: a cohort study of children born very preterm at 5-years.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  5. Review
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  11. Review
  12. Article
  13. Article
  14. Observational
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jessica B GiraultCarolina Institute for Developmental Disabilities, The University of North Carolina at Chapel Hill School of Medicine, 101 Renee Lynne Court, Chapel Hill, NC 27599, USA. Electronic address: jbgirault@unc.edu.
Joseph PivenCarolina Institute for Developmental Disabilities, The University of North Carolina at Chapel Hill School of Medicine, 101 Renee Lynne Court, Chapel Hill, NC 27599, USA.
University of North Carolina at Chapel Hill · US

Funding

Cellular and molecular mechanisms governing cortical surface area overgrowth in iPSC-derived neural cells from longitudinally characterized individuals with autismR01HD055741 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph Piven · 2007 to 2026
$52.6M
UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Hazel B Nichols · 2001 to 2026
$36.3M
MRI-Based Presymptomatic Prediction of ASD, and Early Infant to School-Age Brain-Behavior Trajectories, Mechanisms, and Related OutcomesR01MH118362 · NIMH · WASHINGTON UNIVERSITY · PI John R Pruett · 2019 to 2026
$16.3M
Preclinical CoreP50HD103573 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GABRIEL S DICHTER · 2020 to 2026
$9.7M
Postdoctoral Research in Neurodevelopmental DisordersT32HD040127 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BENJAMIN D PHILPOT, Mark D Shen · 2001 to 2026
$8.5M
Preclinical CoreU54HD079124 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MOY, SHERYL S · 2013 to 2019
$8.0M
Emotion-Modulated Psychophysiology of Autism Spectrum DisordersR21MH085254 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BENNING, STEPHEN D, DICHTER, GABRIEL S · 2009 to 2010
$416k
NICHD NIH HHS P50 HD103573NICHD NIH HHS R01 HD055741NICHD NIH HHS T32 HD040127NICHD NIH HHS U54 HD079124NIEHS NIH HHS P30 ES010126NIMH NIH HHS R01 MH118362NIMH NIH HHS R21 MH085254
6 · The paper itself

Abstract

Autism spectrum disorder (ASD) emerges during early childhood and is marked by a relatively narrow window in which infants transition from exhibiting normative behavioral profiles to displaying the defining features of the ASD phenotype in toddlerhood. Prospective brain imaging studies in infants at high familial risk for autism have revealed important insights into the neurobiology and developmental unfolding of ASD. In this article, we review neuroimaging studies of brain development in ASD from birth through toddlerhood, relate these findings to candidate neurobiological mechanisms, and discuss implications for future research and translation to clinical practice.

Indexed as

Autism Spectrum DisorderBrainChild, PreschoolHumansInfantInfant, NewbornMagnetic Resonance ImagingNeuroimagingPrognosisProspective StudiesAutism spectrum disorderBrainDiffusion tensor imagingInfantMR imagingNeurodevelopmentNeuroimagingPsychoradiology

Identifiers

PMID31759576
PMCPMC6878903
OpenAlexW2987059389

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.