Evidence map›Paper›PMID 31770578›Full record

ArticleCellular signalling2020

l-ornithine activates Ca

Samuel Shin, Farai C Gombedza, Bidhan C Bandyopadhyay

Open access · greenAbstract read
In one paragraph

Article in Cellular signalling, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. OrnipuralAntioxidants (Basel, Switzerland) · 2022
    Article
  12. Hypercalciuria switches CaGenes & diseases · 2022
    Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Samuel ShinCalcium Signaling Laboratory, Research Service, Veterans Affairs Medical Center, 50 Irving Street, NW, Washington, DC 20422, USA.
Farai C GombedzaCalcium Signaling Laboratory, Research Service, Veterans Affairs Medical Center, 50 Irving Street, NW, Washington, DC 20422, USA.
Bidhan C BandyopadhyayCalcium Signaling Laboratory, Research Service, Veterans Affairs Medical Center, 50 Irving Street, NW, Washington, DC 20422, USA; Division of Renal Diseases & Hypertension, Department of Medicine, The George Washington University, Washington, DC 20037, USA; Department of Biomedical Engineering, The Catholic University of America, 620 Michigan Avenue NE, Washington, DC 20064, USA. Electronic address: bidhan.bandyopadhyay@va.gov.
Veterans Health Administration · USUniversity of America · US

Funding

Calcium transport in kidney proximal tubule and calcium phosphate stone formationR01DK102043 · NIDDK · INSTITUTE FOR CLINICAL RESEARCH, INC. · PI BANDYOPADHYAY, BIDHAN CHANDRA · 2015 to 2019
$1.1M
Mechanism of calcium phosphate stone formation in engineered 3D tubuleR21EB021483 · NIBIB · UNIV OF MARYLAND, COLLEGE PARK · PI NIE, ZHIHONG · 2016 to 2017
$385k
NIBIB NIH HHS R21 EB021483NIDDK NIH HHS R01 DK102043
6 · The paper itself

Abstract

Oxidative stress and reactive oxygen species (ROS) generation can be influenced by G-protein coupled receptor (GPCR)-mediated regulation of intracellular Ca

Indexed as

CalciumCalcium SignalingCell DeathCell LineCytoprotectionFluorescenceGTP-Binding ProteinsHumansKidney Tubules, ProximalOrnithineOxidative Stressp38 Mitogen-Activated Protein KinasesPhosphorylationProtective AgentsReactive Oxygen SpeciesReceptors, Calcium-SensingCalciumGTP-Binding ProteinsOrnithinep38 Mitogen-Activated Protein KinasesProtective AgentsReactive Oxygen SpeciesReceptors, Calcium-SensingTRPC Cation ChannelsCa(2+)-sensing receptorCa(2+) signalingCell death protectionl-Amino acidsOxidative stressProximal tubular cells

Identifiers

PMID31770578
PMCPMC7302702
OpenAlexW2991548358

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.