ArticleNutrients2019
Threshold-Effect Association of Dietary Cholesterol Intake with Dyslipidemia in Chinese Adults: Results from the China Health and Nutrition Survey in 2015.
Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 28 citations in OpenAlex.
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- Association of dietary diversity measured by the number of dishes with cardiovascular risk factors among Japanese adults: findings from the National Health and Nutrition Survey, 2018-19.Nutrition journal · 2026Article
- Dietary cholesterol impairs cognition via gut microbiota-derived deoxycholic acid in obese mice.Gut microbes · 2025Article
- Case Report: Spontaneous pregnancy after fertility-preserving treatment in a patient with low-grade endometrial stromal sarcoma and literature review.Frontiers in oncology · 2025Article
- LDL-C rebound after long-term evolocumab treatment and intravascular imaging evidence in a familial hypercholesterolemia patient with early-onset myocardial infarction.Chronic diseases and translational medicine · 2024Article
- Associations between Cholesterol Intake, Food Sources and Cardiovascular Disease in Chinese Residents.Nutrients · 2024Article
- Association between cooking patterns and the prevalence of hyperlipidemia in Eastern China.BMC public health · 2024Article
- Egg consumption and risk of cardiovascular disease: a PERSIAN cohort-based study.BMC cardiovascular disorders · 2023Article
- Higher Adherence to the AMED, DASH, and CHFP Dietary Patterns Is Associated with Better Cognition among Chinese Middle-Aged and Elderly Adults.Nutrients · 2023Article
- Crossover point and maximal fat oxidation training effects on blood lipid metabolism in young overweight women: a pilot study.Frontiers in physiology · 2023Article
- L-shaped association between dietary zinc intake and the risk of developing cardiovascular disease in Chinese adults: A cohort study.Frontiers in nutrition · 2023Article
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- Association between egg consumption and arterial stiffness: a longitudinal study.Nutrition journal · 2021Article
- Influence of Habitual Dairy Food Intake on LDL Cholesterol in a Population-Based Cohort.Nutrients · 2021Article
- Consumption of animal and plant foods and risk of left ventricular diastolic dysfunction: the Bogalusa Heart Study.ESC heart failure · 2020Article
- Article
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8 authors at 1 institution in 1 country.
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Abstract
The association of dietary cholesterol intake with dyslipidemia and subtypes is controversial. This study aimed to examine the association of dietary cholesterol intake with dyslipidemia and subtypes in Chinese adults. Using data from the China Health and Nutrition Survey (CHNS) in 2015, the present study selected 4383 participants aged 18-59 years who were free of diabetes, apoplexy, and myocardial infarction disease. Information was obtained on dietary intake, anthropometric measurements, and blood laboratory measurements. Dietary cholesterol intake was calculated based on the data collected by consecutive 3 days 24 h recalls combined with the weighing of household seasonings and categorized by 11 levels: The first 10 levels in ranges of 50 mg/day and the 11th level at ≥500 mg/day. Dyslipidemia, hypercholesterolemia, hypertriglyceridemia, low-density lipoprotein (LDL)-hypercholesterolemia, and high-density lipoprotein (HDL)-hypocholesterolemia were defined based on the Chinese adult dyslipidemia prevention guide (2016 edition). Multivariable logistic regressions were performed to examine the association of dietary cholesterol intake levels with dyslipidemia and subtypes. The prevalence of dyslipidemia was 37.5% among Chinese adults in 2015 (hypercholesterolemia 9.6%, HDL-hypocholesterolemia 21.1%, LDL-hypercholesterolemia 12.7%, and hypertriglyceridemia 15.2%). The lowest prevalence of hypercholesterolemia and LDL-hypercholesterolemia was 6.7% and 9.4%, respectively, which was relative to a dietary cholesterol intake level of 100.0 to <150.0 mg/day. After adjusting for all potential confounders, adults with the highest dietary cholesterol intake level of ≥500 mg/day compared with the dietary cholesterol intake of 100.0 to <150.0 mg/day showed one-time higher odds of hypercholesterolemia (odds ratios (OR) 2.0, 95% confidence intervals (CI) 1.3-3.3), as well as LDL-hypercholesterolemia (OR 2.0, 95% CI 1.3-3.0), but a null association of dietary cholesterol intake with dyslipidemia, hypertriglyceridemia, and HDL-hypocholesterolemia. The study suggested that a dietary cholesterol intake level of 500 mg/day and above may be a threshold point for high odds of hypercholesterolemia and LDL-hypercholesterolemia.
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