Evidence map›Paper›PMID 31799707›Full record

Trial reportNMR in biomedicine2020

Feasibility of coronary endothelial function assessment using arterial spin labeled CMR.

Ahsan Javed, Andrew Yoon, Steven Cen, Krishna S Nayak, Parveen Garg

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in NMR in biomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ahsan JavedMing Hsieh Department of Electrical and computer Engineering, University of Southern California, Los Angeles, California, USA.ORCID 0000-0003-1311-1247
Andrew YoonDivision of Cardiovascular Medicine, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Steven CenDepartment of Neurology and Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Krishna S NayakMing Hsieh Department of Electrical and computer Engineering, University of Southern California, Los Angeles, California, USA.ORCID 0000-0001-5735-3550
Parveen GargDivision of Cardiovascular Medicine, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
University of Southern California · US

Funding

Novel Myocardial Perfusion Stress Test using Arterial Spin LabelingR01HL130494 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI NAYAK, KRISHNA S · 2016 to 2019
$1.7M
NHLBI NIH HHS R01 HL130494
6 · The paper itself

Abstract

Coronary endothelial dysfunction (CED) is an independent predictor of cardiovascular disease, but its assessment has been limited to invasive coronary angiography. Myocardial perfusion imaging using arterial spin labeled (ASL) cardiac magnetic resonance (CMR) may be an effective non-invasive alternative for detection of CED. Thirty-four patients were recruited: 10 healthy volunteers, 13 at high-risk for coronary artery disease (CAD), and 11 with established CAD. ASL-CMR was performed continuously in a single mid-short axis slice during rest, stress, and recovery. Stress was induced with sustained isometric handgrip exercise, an endothelial dependent stressor. Myocardial perfusion (MP) during rest, peak stress, and recovery were calculated and compared. After excluding subjects unable to complete the protocol or who exhibited poor data quality, 6 healthy, 10 high-risk, and 7 CAD patients were included in the analysis. Average MP (ml/g/min) was 1.31 ± 1.23, 1.61 ± 1.12, and 1.40 ± 0.97 at rest, and 1.64 ± 1.49, 2.31 ± 1.61, and 2.84 ± 1.77 during stress, for the CAD, high-risk and healthy group, respectively. The average MP response (MP

Indexed as

Magnetic Resonance Imaging, CineSpin LabelsAdultAgedCoronary VesselsEndothelium, VascularFeasibility StudiesFemaleHeart RateHumansMaleMiddle AgedMyocardiumPerfusionRestSignal-To-Noise RatioSpin Labelsapplicationscardiovascular MR (CMR) methodshuman studyischemic heart diseasemethods and engineeringmyocardial perfusionperfusion and permeability methodsperfusion spin labeling methods

Identifiers

PMID31799707
PMCPMC6980265
OpenAlexW2991694331

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.