Evidence map›Paper›PMID 31808000›Full record

SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2020

The role of virtual reality on outcomes in rehabilitation of Parkinson's disease: meta-analysis and systematic review in 1031 participants.

Joseph Triegaardt, Thang S Han, Charif Sada, Sapna Sharma, Pankaj Sharma

Erratum issuedOpen access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 50 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 14 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 14 syntheses or guidelines pooled it, 122 citations in OpenAlex.

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  12. Effects of virtual reality in post-stroke aphasia: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
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  16. Sequential motor learning transfers from real to virtual environment.Journal of neuroengineering and rehabilitation · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Joseph TriegaardtInstitute of Cardiovascular Research Royal Holloway, University of London, Egham, Surrey, TW20 0EX, UK.
Thang S HanInstitute of Cardiovascular Research Royal Holloway, University of London, Egham, Surrey, TW20 0EX, UK. thang.han@rhul.ac.uk.ORCID http://orcid.org/0000-0003-2570-0938
Charif SadaInstitute of Cardiovascular Research Royal Holloway, University of London, Egham, Surrey, TW20 0EX, UK.
Sapna SharmaInstitute of Cardiovascular Research Royal Holloway, University of London, Egham, Surrey, TW20 0EX, UK.
Pankaj SharmaInstitute of Cardiovascular Research Royal Holloway, University of London, Egham, Surrey, TW20 0EX, UK. pankaj.sharma@rhul.ac.uk.
Royal Holloway University of London · GBImperial College Healthcare NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionParkinson's disease (PD) is managed primarily by dopamine agonists and physiotherapy while virtual reality (VR) has emerged recently as a complementary method. The present study reviewed the effectiveness of VR in rehabilitation of patients with PD.

methodsLiterature search up to June 2019 identified ten studies (n = 343 participants) suitable for meta-analysis and 27 studies (n = 688 participants) for systematic review. Standard mean difference (SMD) and 95% confidence intervals (CI) were calculated using a random effects model.

resultsIn meta-analysis, compared with active rehabilitation intervention, VR training led to greater improvement of stride length, SMD = 0.70 (95%CI = 0.32-1.08, p = 0.0003), and was as effective for gait speed, balance and co-ordination, cognitive function and mental health, quality of life and activities of daily living. Compared with passive rehabilitation intervention, VR had greater effects on balance: SMD = 1.02 (95%CI = 0.38-1.65, p = 0.002). Results from single randomised controlled trials showed that VR training was better than passive rehabilitation intervention for improving gait speed SMD = 1.43 (95%CI = 0.51-2.34, p = 0.002), stride length SMD = 1.27 (95%CI = 0.38-2.16, p = 0.005) and activities of daily living SMD = 0.96 (95%CI = 0.02-1.89). Systematic review showed that VR training significantly (p < 0.05) improved motor function, balance and co-ordination, cognitive function and mental health, and quality of life and activities of daily living.

conclusionVR used in rehabilitation for patients with PD improves a number of outcomes and may be considered for routine use in rehabilitation.

Indexed as

Motor ActivityOutcome Assessment, Health CarePostural BalanceQuality of LifeVirtual RealityBehavioral SymptomsCognitive DysfunctionGait Disorders, NeurologicHumansNeurological RehabilitationParkinson DiseaseCognitive functionNeurological disordersPhysical functionQuality of life

Identifiers

PMID31808000
PMCPMC7040061
OpenAlexW2994003052

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.