Evidence mapPaperPMID 31812228Full record

SynthesisThe American journal of cardiology2020

Meta-Analysis Comparing Complete Versus Infarct-Related Artery Revascularization in Patients With ST-Elevation Myocardial Infarction and Multivessel Coronary Disease.

Mohammed Osman, Safi U Khan, Peter D Farjo, Noor Chima, Babikir Kheiri, Firas Zahr, Mohamad Alkhouli

Abstract readMeta-Analysis
In one paragraph

Synthesis in The American journal of cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Multivessel versus culprit-only PCI in STEMI patients with multivessel disease: meta-analysis of randomized controlled trials.Clinical research in cardiology : official journal of the German Cardiac Society · 2020
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohammed OsmanDivision of Cardiology, West Virginia University School of Medicine, Morgantown, West Virginia.
Safi U KhanDivision of Cardiology, West Virginia University School of Medicine, Morgantown, West Virginia.
Peter D FarjoDivision of Cardiology, West Virginia University School of Medicine, Morgantown, West Virginia.
Noor ChimaDivision of Cardiology, West Virginia University School of Medicine, Morgantown, West Virginia.
Babikir KheiriKnight Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon.
Firas ZahrKnight Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon.
Mohamad AlkhouliDepartment of Cardiovascular Diseases, Mayo Clinic School of Medicine, Rochester, Minnesota. Electronic address: alkhouli.mohamad@mayo.edu.

Funding

West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve HealthU54GM104942 · WEST VIRGINIA UNIVERSITY · 2025 to 2025
$4.0M
NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

A strategy of complete revascularization (CR) versus infarct-related artery revascularization (IRA) in patients with ST-elevation myocardial infarction (STEMI) continues to be a subject of debate. We performed an updated meta-analysis to compare the 2 strategies. Outcomes of interest included major adverse cardiovascular events (MACE), cardiovascular mortality, all-cause mortality, stroke, repeat revascularization, myocardial infarction, and contrast-induced nephropathy. Ten randomized trials including 7,423 patients (CR = 3,574 and IRA = 3,849), with a follow-up of 2.0 ± 0.8 years were included. There was a significant reduction in MACE with CR versus IRA (10.7% vs 18.6%, relative risk [RR] 0.64, 95% confidence interval [CI] 0.51 to 0.81, p = 0.002, I

Indexed as

Coronary Artery DiseaseHumansMyocardial RevascularizationST Elevation Myocardial Infarction

Identifiers

PMID31812228
PMCPMC7453957

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.