Evidence mapPaperPMID 31824340Full record

ArticleFrontiers in physiology2019

Mineralocorticoid Receptor-Dependent Impairment of Baroreflex Contributes to Hypertension in a Mouse Model of Primary Aldosteronism.

Luo Shi, Fang Yuan, Xuefang Wang, Ri Wang, Kun Liu, Yanming Tian, Zan Guo, Xiangjian Zhang, Sheng Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Luo ShiDepartment of Physiology, Hebei Medical University, Shijiazhuang, China.
Fang YuanDepartment of Physiology, Hebei Medical University, Shijiazhuang, China.
Xuefang WangDepartment of Physiology, Hebei North University, Zhangjiakou, China.
Ri WangDepartment of Physiology, Hebei Medical University, Shijiazhuang, China.
Kun LiuDepartment of Laboratory Medicine, Hebei University of Chinese Medicine, Shijiazhuang, China.
Yanming TianDepartment of Physiology, Hebei Medical University, Shijiazhuang, China.
Zan GuoDepartment of Physiology, Hebei Medical University, Shijiazhuang, China.
Xiangjian ZhangHebei Key Laboratory of Vascular Homeostasis and Hebei Collaborative Innovation Center for Cardio-Cerebrovascular Disease, Second Hospital of Hebei Medical University, Shijiazhuang, China.
Sheng WangDepartment of Physiology, Hebei Medical University, Shijiazhuang, China.
Hebei Medical University · CNHebei North University · CNHebei University of Chinese Medicine · CNSecond Hospital of Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary aldosteronism (PA) is the most common cause of secondary hypertension. The paucity of good animal models hinders our understanding of the pathophysiology of PA and the hypertensive mechanism of PA remains incompletely known. It was recently reported that genetic deletion of TWIK-related acid-sensitive potassium-1 and potassium-3 channels from mice (TASK

Indexed as

aldosteronealdosteronismbaroreflexhypertensionmineralocorticoid receptor

Identifiers

PMID31824340
PMCPMC6883352
OpenAlexW2990673639

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.