Evidence map›Paper›PMID 31831574›Full record

Trial reportHeart (British Cardiac Society)2020

Reducing weight and increasing physical activity in people at high risk of cardiovascular disease: a randomised controlled trial comparing the effectiveness of enhanced motivational interviewing intervention with usual care.

Khalida Ismail, Adam Bayley, Katherine Twist, Kurtis Stewart, Katie Ridge, Emma Britneff, Anne Greenough, Mark Ashworth, Jennifer Rundle, Derek G Cook and 5 more

Abstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Heart (British Cardiac Society), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Behaviour change interventions to improve physical activity in adults: a systematic review of economic evaluations.The international journal of behavioral nutrition and physical activity · 2024
    Pooled it
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  6. The Role of Physical Activity in Long-term Weight Loss: 36-month Results From a Randomized Controlled Trial.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023
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  18. The MIPAM trial - motivational interviewing and physical activity monitoring to enhance the daily level of physical activity among older adults - a randomized controlled trial.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Khalida IsmailDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK khalida.2.ismail@kcl.ac.uk.
Adam BayleyDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Katherine TwistDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Kurtis StewartDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID 0000-0003-3730-9733
Katie RidgeDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Emma BritneffDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Anne GreenoughDepartment of Women and Children's Health, School of Life Course Sciences, King's College London, London, UK.
Mark AshworthSchool of Population Health and Environmental Sciences, King's College London, London, London, UK.
Jennifer RundleDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Derek G CookDivision of Population Health Sciences and Education, University of London St George's Molecular and Clinical Sciences Research Institute, London, UK.
Peter WhincupDivision of Population Health Sciences and Education, University of London St George's Molecular and Clinical Sciences Research Institute, London, UK.
Janet TreasureDepartment of Health Services and Population Research, Institute of Psychiatry, King's College London, London, UK.
Paul McCroneSection of Eating Disorders, Institute of Psychiatry, King's College London, London, UK.
Kirsty WinkleyFlorence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK.
Daniel StahlDepartment of Biostatistics and Health Informatics, Institute of Psychiatry, King's College London, London, UK.

Funding

Department of Health 10/62/03Medical Research Council G1000758
6 · The paper itself

Abstract

objectiveThe epidemic of obesity is contributing to the increasing prevalence of people at high risk of cardiovascular disease (CVD), negating the medical advances in reducing CVD mortality. We compared the clinical and cost-effectiveness of an intensive lifestyle intervention consisting of enhanced motivational interviewing in reducing weight and increasing physical activity for patients at high risk of CVD.

methodsA three-arm, single-blind, parallel-group randomised controlled trial was conducted in consenting primary care centres in south London. We recruited patients aged 40-74 years with a QRisk2 score ≥20.0%, which indicates the probability of having a CVD event in the next 10 years. The intervention was enhanced motivational interviewing which included additional behaviour change techniques and was delivered by health trainers in 10 sessions over 1 year, in either group (n=697) or individual (n=523) format. The third arm received usual care (UC; n=522). The primary outcomes were physical activity (mean steps/day) and weight (kg). Secondary outcomes were changes in low-density lipoprotein cholesterol and CVD risk score. We estimated the relative cost-effectiveness of each intervention.

resultsAt 24 months, the group and individual interventions were not more effective than UC in increasing physical activity (mean difference=70.05 steps, 95% CI -288.00 to 147.90 and mean difference=7.24 steps, 95% CI -224.01 to 238.50, respectively), reducing weight (mean difference=-0.03 kg, 95% CI -0.49 to 0.44 and mean difference=-0.42 kg, 95% CI -0.93 to 0.09, respectively) or improving any secondary outcomes. The group and individual interventions were not cost-effective at conventional thresholds.

conclusionsEnhancing motivational interviewing with additional behaviour change techniques was not effective in reducing weight or increasing physical activity in those at high CVD risk.

Indexed as

ExerciseMotivational InterviewingWeight LossAdultAgedCardiovascular DiseasesFemaleHumansMaleMiddle AgedRisk AssessmentSingle-Blind MethodTreatment Outcomebehaviour change techniquescardiovascular diseaselifestyle interventionmotivational interviewingphysical activityprimary careweight loss

Identifiers

PMID31831574
PMCPMC7057797

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.