Evidence map›Paper›PMID 31847788›Full record

ArticleOpen biology2019

Transcriptomic analysis and novel insights into lens fibre cell differentiation regulated by Gata3.

Elena Martynova, Yilin Zhao, Qing Xie, Deyou Zheng, Ales Cvekl

Open access · goldAbstract read
In one paragraph

Article in Open biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Elena MartynovaDepartments of Ophthalmology and Visual Sciences and Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Yilin ZhaoDepartments of Ophthalmology and Visual Sciences and Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Qing XieDepartments of Ophthalmology and Visual Sciences and Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Deyou ZhengDepartments of Genetics, Neurology, and Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Ales CveklDepartments of Ophthalmology and Visual Sciences and Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Albert Einstein College of Medicine · US

Funding

PAX-6 AS A KEY REGULATOR OF LENS DEVELOPMENTR01EY012200 · NEI · YESHIVA UNIVERSITY · PI CVEKL, ALES · 2000 to 2025
$13.1M
NEI NIH HHS R01 EY012200
6 · The paper itself

Abstract

Gata3 is a DNA-binding transcription factor involved in cellular differentiation in a variety of tissues including inner ear, hair follicle, kidney, mammary gland and T-cells. In a previous study in 2009, Maeda

Indexed as

Gene Expression ProfilingGene Expression RegulationTranscriptomeAllelesAnimalsCell DifferentiationCyclin-Dependent Kinase Inhibitor p27Cyclin-Dependent Kinase Inhibitor p57GATA3 Transcription FactorImmunohistochemistryLens, CrystallineMiceMice, KnockoutMice, TransgenicModels, BiologicalMutationCdkn1b protein, mouseCdkn1c protein, mouseCyclin-Dependent Kinase Inhibitor p27Cyclin-Dependent Kinase Inhibitor p57Gata3 protein, mouseGATA3 Transcription FactorCdkn1b/p27Cdkn1c/p57differentiationGata3lensProx1

Identifiers

PMID31847788
PMCPMC6936257
OpenAlexW2994768306

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.