Evidence map›Paper›PMID 31860441›Full record

ArticleMicrobial genomics2020

Landscape of gene expression variation of natural isolates of

Chen-Hsin Yu, Yuan Chen, Christopher A Desjardins, Jennifer L Tenor, Dena L Toffaletti, Charles Giamberardino, Anastasia Litvintseva, John R Perfect, Christina A Cuomo

Open access · goldAbstract read
In one paragraph

Article in Microbial genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Peroxisomes regulate virulence and cell density sensing inbioRxiv : the preprint server for biology · 2025
    Article
  6. Cryptococcal nutrient acquisition and pathogenesis: dining on the host.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  7. Article
  8. Is Cryptococcus neoformans a pleomorphic fungus?Current opinion in microbiology · 2024
    Review
  9. Exposure of Cryptococcus neoformans to low nitrogen levels enhances virulence.International microbiology : the official journal of the Spanish Society for Microbiology · 2024
    Article
  10. Article
  11. Comparative genomics ofbioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Importance of Clinical Isolates inJournal of fungi (Basel, Switzerland) · 2023
    Review
  16. microLife · 2022
    Article
  17. Long Non-Coding RNAs inFrontiers in cellular and infection microbiology · 2022
    Article
  18. Article
  19. Article
  20. Fungicidal Activity of Recombinant Javanicin againstMolecules (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Chen-Hsin YuDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.
Yuan ChenDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.
Christopher A DesjardinsBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Jennifer L TenorDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.
Dena L ToffalettiDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.
Charles GiamberardinoDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.
Anastasia LitvintsevaMycotic Diseases Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
John R PerfectDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.
Christina A CuomoBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Duke University · USBroad Institute · USCenters for Disease Control and Prevention · US

Funding

Large Scale Sequencing and Analysis of GenomesU54HG003067 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GABRIEL, STACEY, LANDER, ERIC S · 2004 to 2015
$568.6M
Viral Genomics: evolution, spread, and host interactionsU19AI110818 · NIAID · BROAD INSTITUTE, INC. · PI BIRREN, BRUCE W., NEAFSEY, DANIEL E · 2014 to 2024
$66.5M
Pathobiology of C. neoformans in the Central Nervous SystemR01AI073896 · NIAID · DUKE UNIVERSITY · PI PERFECT, JOHN R. · 2008 to 2018
$4.4M
Evolution of Cryptococcus neoformans Strains from Patients with HIV/AIDSR01AI093257 · NIAID · DUKE UNIVERSITY · PI PERFECT, JOHN R. · 2011 to 2022
$3.8M
NHGRI NIH HHS U54 HG003067NIAID NIH HHS R01 AI073896NIAID NIH HHS R01 AI093257NIAID NIH HHS U19 AI110818
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression Regulation, FungalAnimalsCell LineCryptococcus neoformansMiceRNA-SeqStress, PhysiologicalTranscriptomeVirulencecerebrospinal fluid (CSF)CryptococcusmacrophageRNA-Seq

Identifiers

PMID31860441
PMCPMC7067042
OpenAlexW2995375854

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.