Evidence map›Paper›PMID 31865607›Full record

SynthesisJournal of nephrology2020

Intradialytic training in patients with end-stage renal disease: a systematic review and meta-analysis of randomized clinical trials assessing the effects of five different training interventions.

Filipe Ferrari, Lucas Helal, Thiago Dipp, Douglas Soares, Ângela Soldatelli, Andrew Lee Mills, Cláudio Paz, Mário César Carvalho Tenório, Marcelo Trotte Motta, Franklin Correa Barcellos and 1 more

Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05207527 (Design and Effectiveness of Different Physical Exercise-based Interventions About Health Indicators and Quality of Life in Patients With Chronic Kidney Disease in Hemodialysis), which is not on this map. Cited by 36 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 9 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05207527 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Design and Effectiveness of Different Physical Exercise-based Interventions About Health Indicators and Quality of Life in Patients With Chronic Kidney Disease in Hemodialysis

TypeinterventionalSponsorUniversidad del RosarioRan2025 to 2028Enrolled120ConditionsChronic Kidney DiseasesArmscardiovascular exercise, Muscle strength, Mixed
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 9 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Effects of intradialytic exercise on health-related quality of life in patients undergoing maintenance haemodialysis: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Pooled it
  7. Exercise training for adults undergoing maintenance dialysis.The Cochrane database of systematic reviews · 2022
    Pooled it
  8. Pooled it
  9. Pooled it
  10. Trial
  11. Addition of Neuromuscular Electrical Stimulation, Based on the Level of Excitability, to an Intradialytic Twice-Weekly Cycling Protocol: A Randomized Trial.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Trial
  12. Trial
  13. Trial
  14. Trial
  15. Review
  16. Lifestyle and Environment Aspects Challenging Kidney Health.Kidney & blood pressure research · 2026
    Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Filipe FerrariGraduate Program in Cardiology and Cardiovascular Sciences, School of Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2350-Santa Cecília, Porto Alegre, RS, 90035-003, Brazil.ORCID http://orcid.org/0000-0001-6929-8392
Lucas HelalGraduate Program in Cardiology and Cardiovascular Sciences, School of Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2350-Santa Cecília, Porto Alegre, RS, 90035-003, Brazil.
Thiago DippSchool of Physical Therapy, Universidade do Vale do Rio dos Sinos, São Leopoldo, Brazil.
Douglas SoaresGraduate Program in Cardiology and Cardiovascular Sciences, School of Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2350-Santa Cecília, Porto Alegre, RS, 90035-003, Brazil.
Ângela SoldatelliExact Sciences and Engineering, Universidade de Caxias do Sul, Caxias do Sul, Brazil.
Andrew Lee MillsCenter for Workplace Health, American Heart Association, Houston, TX, USA.
Cláudio PazFaculdade Social da Bahia, Bahia, Brazil.
Mário César Carvalho TenórioFaculdade Social da Bahia, Bahia, Brazil.
Marcelo Trotte MottaDepartment of Biotechnology, Universidade Estadual de Feira de Santana, Feira de Santana, Brazil.
Franklin Correa BarcellosDepartment of Nephrology, Universidade Católica de Pelotas, Pelotas, Brazil.
Ricardo SteinGraduate Program in Cardiology and Cardiovascular Sciences, School of Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2350-Santa Cecília, Porto Alegre, RS, 90035-003, Brazil. rstein@cardiol.br.
Universidade Federal do Rio Grande do Sul · BRAmerican Heart Association · USUniversidade Católica de Pelotas · BRUniversidade de Caxias do Sul · BRUniversidade do Vale do Rio dos Sinos · BRUniversidade Estadual de Feira de Santana · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePatients with end-stage renal disease (ESRD) undergoing hemodialysis may have reduced dialysis adequacy (Kt/V), low cardiorespiratory fitness, and worse prognosis. Different types of intradialytic training (IDT) may serve as an adjunct therapy for the management of the ESRD. This systematic review and meta-analysis aimed to assess the impact of different types of IDT on clinical outcomes and functional parameters in ESRD.

methodsPubMed, Embase, CINAHL, Cochrane CENTRAL, Scopus, SPORTDiscus, and Google Scholar were searched for randomized clinical trials in adult patients with ESRD which compared IDT with usual care (UC), without language restrictions and published up to July 2019; a handsearch of references was also performed. Certainty of evidence was assessed using GRADE, and risk of bias in primary studies with the RoB 1.0 tool.

resultsFifty studies were included (n = 1757). Compared to UC, aerobic IDT improved Kt/V (WMD = 0.08), VO

conclusionsAerobic, resistance, and combined training during hemodialysis, as well as FES and IMT, demonstrated to be effective for the treatment of the patient with ESRD. Our data should be interpreted in light of the unclear risk of bias of most evaluated articles and the low to very low certainty of evidence for evaluated outcomes. PROSPERO REGISTRATION ID: CRD42017081338. DATA SHARING REPOSITORY: https://osf.io/fpj54/.

Indexed as

ExerciseRenal DialysisHumansKidney Failure, ChronicDialysis efficacyEnd-stage renal diseaseIntradialytic exerciseMeta-analysis

Identifiers

PMID31865607
OpenAlexW2996415997

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.