SynthesisMolecular genetics & genomic medicine2020
The role of race and ethnicity in views toward and participation in genetic studies and precision medicine research in the United States: A systematic review of qualitative and quantitative studies.
Synthesis in Molecular genetics & genomic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
57 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Preferences for genetic testing among populations underrepresented in genomic research: a systematic review.European journal of human genetics : EJHG · 2025Pooled it
- Pooled it
- Attitudes and beliefs regarding race-targeted genetic testing of Black people: A systematic review.Journal of genetic counseling · 2023Pooled it
- The role of race and ethnicity in views toward and participation in genetic studies and precision medicine research in the United States: A systematic review of qualitative and quantitative studies.Molecular genetics & genomic medicine · 2020Pooled it
- The Trial Enrollment Diversity Dashboard for Acute Leukemia Clinical Research: Intervention Development and Cohort Analysis.JCO oncology practice · 2025Trial
- Social vulnerability and genetic service utilization among unaffected BRIDGE trial patients with inherited cancer susceptibility.BMC cancer · 2025Trial
- Comparing models of delivery for cancer genetics services among patients receiving primary care who meet criteria for genetic evaluation in two healthcare systems: BRIDGE randomized controlled trial.BMC health services research · 2021Trial
- Healthcare experiences and the cycle of genomic healthcare disparities: A cross-sectional study utilizing the 'All of Us' research program.Journal of community genetics · 2026Article
- "Es Lindo, Pero Estamos Perdidos"-Characterizing Facilitators and Barriers to Clinical Genetic Testing for Latino Populations.Journal of racial and ethnic health disparities · 2026Article
- Returning value to communities from the All of Us Research Program through the lens of social determinants of health and ethical, legal, and social implications.International journal for equity in health · 2026Review
- Self-collected biospecimen consent and return rates in a population-based study among women with ovarian cancer: insights from the ORCHiD study.Cancer causes & control : CCC · 2026Article
- Strategies to build trustworthiness and increase diversity in colorectal cancer biospecimen research: a multi-phase, multi-site qualitative study.Journal of community genetics · 2026Article
- Perceptions of and willingness to participate in genomics research among a U.S. sample.Frontiers in genetics · 2026Article
- Development and psychometric evaluation of a new genetic attitudes questionnaire in two national samples of United States residents.Scientific reports · 2025Article
- Factors influencing trustworthiness and perceived biases of medical information and genetic testing for Black and White Americans.PLoS genetics · 2025Article
- Parental knowledge and attitudes toward genetic counseling and childhood genetic testing for congenital anomalies in Qatar.Journal of genetic counseling · 2025Article
- Rethinking agency for genetic testing intention among Latinos: Determining predictors of intention for carrier screening and cancer predisposition testing.Genetics in medicine : official journal of the American College of Medical Genetics · 2025Article
- How is Value Defined in Molecular Testing in Cancer? A Scoping Review.Applied health economics and health policy · 2025Article
- Underrepresented populations in genomic research: a qualitative study of researchers' perspectives.BMC medical genomics · 2025Article
- Religious factors predict support for genomic medicine more strongly than politics, education, or trust: A survey of 4,939 adults in the United States.Frontiers in genetics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRacial/ethnic minority populations in the United States are consistently underrepresented in genetic research. Large-scale public participation is required to ensure discoveries from precision medicine research are applicable to everyone. To evaluate views toward and facilitators of participation among minority populations in the United States, we conducted a systematic review of literature.
methodsSix databases were searched for articles published from 2005 to 2018 assessing minority populations' views and/or willingness to participate in genetic research. A thematic framework was applied to extracted data to synthesize findings, and the Socio-Ecological Model was used to evaluate papers.
resultsReview of 2,229 titles and abstracts identified 27 papers (n = 8 qualitative, n = 19 quantitative). Themes included knowledge of genetics, engagement in research, facilitators and barriers to participation, and cultural considerations. Understanding of genetics was low, yet the majority of participants were willing to participate in genetic research among all populations included in the literature (range: 57%-97%). Recommendations for research included utilizing community-based participatory approaches, evaluating participants' informational needs, incentivizing participation, and providing direct benefits (e.g., genetic test results).
conclusionResults could influence future study designs that incorporate all levels of the Socio-Ecological Model and better meet the needs of underrepresented groups, thereby ensuring precision medicine research findings are applicable to all.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.