Evidence map›Paper›PMID 31877697›Full record

ArticleAntioxidants (Basel, Switzerland)2019

Antidiabetic Activity of Gold Nanoparticles Synthesized Using Wedelolactone in RIN-5F Cell Line.

Vinayagam Ramachandran, Mariadoss Arokia Vijaya Anand, Ernest David, Karthikkumar Venkatachalam, Shalini Vijayakumar, Vijayalakshmi Sankaran, Agilan Balupillai, Casimeer C Sangeetha, K M Gothandam, Venkata Subbaiah Kotakadi and 3 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Bio-Inspired Synthesis of Gold Nanoparticles Using Leaf Extract ofInternational journal of nanomedicine · 2024
    Article
  7. Experimental Approaches to Diabetes Mellitus.The Eurasian journal of medicine · 2022
    Article
  8. Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 5 countries.

Vinayagam RamachandranDepartment of Biotechnology, Thiruvalluvar University, Vellore 632115, India.ORCID 0000-0003-3568-2358
Mariadoss Arokia Vijaya AnandDepartment of Biotechnology, Thiruvalluvar University, Vellore 632115, India.ORCID 0000-0001-6154-7366
Ernest DavidDepartment of Biotechnology, Thiruvalluvar University, Vellore 632115, India.
Karthikkumar VenkatachalamDepartment of Pharmacology and Therapeutics, College of Medicine of Health Sciences, United Arab Emirates University, Al Ain 17666, UAE.
Shalini VijayakumarDepartment of Biotechnology, Thiruvalluvar University, Vellore 632115, India.
Vijayalakshmi SankaranDepartment of Biotechnology, Thiruvalluvar University, Vellore 632115, India.
Agilan BalupillaiDepartment of Biotechnology, Thiruvalluvar University, Vellore 632115, India.
Casimeer C SangeethaDepartment of Physics, Sri Padmavati Mahila Visvavidyalayam (Women University), Andhra Pradesh 517502, India.
K M GothandamVellore Institute of Technology (VIT), School of Biological Sciences and Technology, Vellore 632104, India.ORCID 0000-0003-1576-5324
Venkata Subbaiah KotakadiDST PURSE Centre, Sri Venkateswara University, Tirupati 517502, Andhra Pradesh, India.
Alaa GhidanPharmacy School, Aqaba University of Technology, Aqaba 77110, Jordan.
Tawfiq Al AntaryDepartment of Plant protection, Faculty of Agriculture, University of Jordan, Amman 11942, Jordan.
Baojun XuFood Science and Technology Program, Beijing Normal University-Hong Kong Baptist University United International College, Zhuhai 519087, Guangdong, China.ORCID 0000-0003-0739-3735
Thiruvalluvar University · INBeijing Normal-Hong Kong Baptist University · CNSri Padmavati Mahila Visvavidyalayam · INSri Venkateswara University · INUnited Arab Emirates University · AEUniversity of Jordan · JOVellore Institute of Technology University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We synthesized the gold nanoparticles (AuNPs) using wedelolactone (WDL) and characterized them using UV-visible spectroscopy, fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopic (SEM), transmission electron microscopic (TEM), energy dispersive X-ray diffraction, and atomic force microscopic (AFM) studies. The electronic spectrum exhibited an absorption peak at 535 nm. The FT-IR results proved that WDL was stabilized on the surface of AuNPs by acting as a capping or reducing agent. The crystalline structure was affirmed by XRD pattern and the spherical shape of WDL-AuNPs was evidenced by SEM, TEM, and AFM. The synthesized WDL-AuNPS were evaluated for anti-diabetic activity in pancreatic RIN-5F cell lines.

Indexed as

antidiabeticcytotoxicitydi-(2-ethylhexyl) phthalategold nanoparticlesRIN-5F cell linewedelolactone

Identifiers

PMID31877697
PMCPMC7023137
OpenAlexW2996675988

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.